Growing evidence from archaic and early modern human genomes brings new insights to the emergence of modern humans. We recount recent information collected from ancient DNA studies that inform us about the evolutionary pathway to modern humanity. These findings point to both individual- and population-level advantages underlying modern human expansion.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.cell.2024.01.047 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Current Applications and Developments of Natural Language Processing in Kidney Transplantation: A Scoping Review.
Transplant Proc
March 2025
Department of Urology, Singapore General Hospital, Singapore, Singapore. Electronic address:
Background And Objective: Natural language processing (NLP) is a subfield of artificial intelligence that enables computers to process human language. As most human interactions today involve the internet and electronic devices, NLP tools quickly become indispensable to modern life. The use of NLP tools in medical practice and research is growing fast.
View Article and Find Full Text PDFSelf-Care Interventions for Children and Young People With Neurodisabilities: A Mixed Methods Study of Current Therapy Practice in the United Kingdom.
Child Care Health Dev
March 2025
Northumbria University, Newcastle upon Tyne, UK.
Background: Self-care is a priority outcome for children and young people with neurodisabilities, their parents and therapists, but there is little evidence about paediatric therapy interventions for children's self-care in the United Kingdom.
Methods: Children with neurodisabilities, parents, therapists and teachers participated in this mixed methods study. Data were collected by interviews and observations of routine therapy appointments.
Reirradiation for Locally Recurrent Head and Neck Cancer: State-of-the-Art and Future Directions.
Semin Radiat Oncol
April 2025
Department of Radiation Oncology, University of Texas, MD Anderson Cancer Center, Houston, TX.
Reirradiation of the head and neck presents one of the most complex and challenging scenarios faced by (for) clinicians due to the narrow therapeutic window. Its use is increasing in clinical practice, often guided by empirical and pragmatic approaches due to the limited availability of high-level evidence from randomized clinical trials. Successful reirradiation requires a precise balance between tumor control probability (TCP) and normal tissue complication probability (NTCP).
View Article and Find Full Text PDFPrinciples and Paradigms of De-Escalated Elective Nodal Irradiation: Boldly Going Towards an Inflection Point in Head and Neck Radiotherapy.
Semin Radiat Oncol
April 2025
Department of Radiation Oncology, University of Toronto, Toronto, Ontario, Canada.; Radiation Medicine Program, Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.. Electronic address:
Fundamental axioms of elective nodal irradiation (ENI) for head and neck cancers merit re-examination in contemporary practice. Standard ENI doses to volumes bordering critical organs-at-risk increased during the transition from two-dimensional radiation planning to intensity-modulated radiotherapy, despite improvements in detection of occult nodal metastases with modern imaging, use of concurrent chemotherapy, and identification of human papillomavirus (HPV)-related radiosensitivity. Historical large ENI volumes covering low-risk nodal regions continue to be commonly used even as awareness grows regarding the predominant pattern-of-failure within existing gross disease.
View Article and Find Full Text PDFHealth implications of established and emerging stressors: design of the prospective New Jersey Population Health Cohort (NJHealth) Study.
BMJ Open
March 2025
Institute for Health, Health Care Policy and Aging Research, Rutgers Health, New Brunswick, New Jersey, USA.
Introduction: Some stressors, like the death of a partner, are common and rigorously studied, while others, such as those related to climate change or social media, are just emerging and in need of systematic research. The New Jersey Population Health Cohort (NJHealth) Study aims to characterise established and emerging stressors and delineate the pathways through which they influence health, especially among groups likely to experience chronic exposure to stressors including immigrants, people of colour, multigenerational families and low-income families.
Methods And Analysis: A prospective cohort, the NJHealth Study is recruiting 8000 NJ residents aged 14 and older using probabilistic and purposive methods to include members of multigenerational families, marginalised racial/ethnic and low-income populations, and recent immigrant groups.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!