Unraveling the complex relationship: Multiple sclerosis, urinary tract infections, and infertility.

Mult Scler Relat Disord

Toxicology Research Center, Medical Basic Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran; Department of Toxicology, Faculty of Pharmacy, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran. Electronic address:

Published: April 2024

AI Article Synopsis

  • Multiple sclerosis (MS) is an immune disorder that causes nerve damage, leading to complications like urinary dysfunction and sexual issues, particularly in younger patients.
  • Despite advancements in MS management over the past 20 years that may slow disease progression, challenges like urinary tract infections (UTIs) and sexual dysfunction persist, highlighting the importance of awareness and early treatment.
  • The article discusses microbial pathogens associated with MS and examines the experiences of individuals with MS who face UTI and infertility problems.

Article Abstract

Background: Multiple sclerosis (MS) is an immune system disorder that affects the central nervous system (CNS) and progressively damages nerve fibers and protective myelin. People with MS often experience a wide range of complications, including lower urinary tract dysfunction, urinary tract infections (UTIs) and sexual dysfunction. MS is common in young people and can lead to sexual dysfunction (SD) and infertility, which becomes more pronounced as the disease progresses.

Results: Over the past two decades, significant advances have been made in the management of MS, which may slow the progression of the disease and alter its course. However, UTI and SD remain significant challenges for these patients. Awareness of the underlying complications of MS, such as UTIs and infertility, is crucial for prevention, early detection and appropriate treatment, as there is a causal relationship between UTIs and the use of corticosteroids during an attack.

Conclusion: This article provides an overview of potential microbial pathogens that contribute to the development of MS, as well as an assessment of people with MS who report UTIs and infertility.

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Source
http://dx.doi.org/10.1016/j.msard.2024.105512DOI Listing

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