AI Article Synopsis
- - Amyloidosis is a rare condition characterized by the buildup of abnormal protein aggregates in body tissues, which can disrupt organ function; localized amyloidosis is generally benign, especially in the head and neck area.
- - In the oral cavity, localized amyloidosis commonly presents as multiple soft nodules on the tongue, lip, and cheek due to these protein deposits.
- - A case study of a one-year-old girl with a smooth nodule in the labial mucosa highlights the importance of ruling out systemic amyloidosis and underlying conditions, with surgical treatment being potentially helpful for functional issues.
Article Abstract
Amyloidosis is a relatively rare condition with an array of complex pathophysiology. Localized amyloidosis is a rare and benign condition that practically never results in any clinical repercussions in the head and neck area. Multiple soft nodules of the tongue, lip, and cheek are the most commonly described defining characteristics of localized oral amyloidosis. These nodules originate due to the proliferation of abnormally folded protein aggregates in the body's extracellular tissue compartments, which destroy organ structure and function. Herein, we address the case of a female infant aged one with a smooth nodule in the labial mucosa who was diagnosed with primary localized amyloidosis. When a patient is diagnosed with amyloidosis of the oral mucosa, the possibility of systemic amyloidosis or an underlying plasma cell dyscrasia must be ruled out. Surgical treatment may be beneficial for eliminating any functional impairment if primary localized amyloidosis is established.
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| http://dx.doi.org/10.4103/ijpm.ijpm_720_23 | DOI Listing |
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