AI Article Synopsis
- - Syringoid eccrine carcinoma (SEC) is a rare and aggressive skin cancer that typically appears as nodules or plaques, often in the head, neck, or trunk, making it challenging to diagnose due to its varied appearance.
- - The cancer exhibits unique growth patterns characterized by infiltrative behavior and potential to spread, with histological features resembling syringomas and showing ductular differentiation.
- - This text discusses a rare case of SEC found in the nipple of a 51-year-old male, marking only the second documented instance of this condition in a male patient, and it was complicated by metastasis to the axillary lymph nodes.
Article Abstract
Syringoid eccrine carcinoma of nipple is an extremely rare neoplasm of adnexal origin with variable clinical appearance and diverse histologic findings. Syringoid eccrine carcinoma (SEC) is often a diagnostic dilemma due to its morphology and presentation. Usually, these malignancies arise as non-ulcerated nodules or plaques in the head & neck region including the trunk. They are locally aggressive and have an infiltrative growth pattern with a propensity for metastasis. SEC is characterized by syringoma-like tadpole morphology with ductular differentiation and predominant desmoplasia. Immunostaining in SEC is variable and this variability is believed to arise from the tumor's ability to differentiate along multiple routes including sweat secretory and or ductal differentiation. Here we present a rare case of SEC/ syringomatous carcinoma of nipple in a 51-year-old male breast with associated axillary lymph node metastasis. As per English literature, this is the second case of SEC in nipple of male patient.
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| http://dx.doi.org/10.4103/ijpm.ijpm_716_23 | DOI Listing |
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