Activated protein C (APC) was shown to release extracellular vesicles (EVs). APC bound to the EVs was thought to be responsible for cytoprotection. Our study demonstrates that the cytoprotective effects of APC-released EVs are independent of APC. APC-released EVs carry anti-inflammatory microRNAs in their cargo.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11103092 | PMC |
| http://dx.doi.org/10.1182/blood.2023023518 | DOI Listing |
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