Two new cassane diterpenoids from the seed kernels of .

Two new cassane diterpenoids, sucupiranin MN () and sucupiranin ML (), together with two known compounds sucutinirane C () and deacetylsucutinirane C () were isolated from the seed kernels of . Their structures were elucidated by means of analysis of comprehensive spectroscopic data, especially HRESIMS and 1D/2D NMR spectroscopy. Compounds are typical furan-type cassane derivatives with an aromatized C ring. Biological evaluation revealed that compounds at the concentration of 10 μM could inhibit the overproduction of NO in LPS-stimulated RAW 264.7 macrophages.