AI Article Synopsis

  • Pancreatic cancer is often diagnosed late, resulting in severe complications like gastric outlet obstruction (GOO), leading to a decline in patients' quality of life due to symptoms like nausea and vomiting.
  • Most patients can't undergo surgery due to the advanced stage of the disease, so treatments focus on palliative care instead.
  • Gastrojejunostomy has been the traditional treatment for GOO, but endoscopic stent placement is an emerging, less invasive option, highlighting the need for further research to determine its best use in advanced pancreatic cancer cases.

Article Abstract

Pancreatic cancer is one of the most fatal malignancies due to its advanced stages at the time of presentation. Often, it is only diagnosed when patients present with late-stage complications, such as gastric outlet obstruction (GOO). Many patients experience a poor quality of life due to the side effects of GOO, such as persistent nausea, vomiting, and an inability to tolerate an oral diet, and as such, patients deteriorate quickly after their diagnosis. Because pancreatic cancer is diagnosed at advanced stages, many patients are not surgical candidates, and thus treatment is tailored for palliative measures. With GOO specifically, gastrojejunostomy has been the mainstay of palliative management; however, endoscopic stent placement is a new, innovative, and minimally invasive alternative option. Herein, we present a case of GOO as a complication of pancreatic adenocarcinoma, treated with palliative endoscopic stent placement. Further research is warranted to identify patients who would most benefit from this modality of palliation in the treatment of advanced pancreatic cancer.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10901673PMC
http://dx.doi.org/10.7759/cureus.53186DOI Listing

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