AI Article Synopsis
- - Steud. is found in Central and South America, referred to as 'salsaparilha' or 'japicanga', and this study analyzed its chemical composition and effects of its ethanol extract (EE) and leaf fractions.
- - Key compounds identified include fatty acid esters, phytol, flavonoids, phenolic compounds, and steroidal saponins, with the highest concentration of flavonoids in the ethyl acetate (AC) fraction.
- - All samples showed antioxidant activity, particularly the AC fraction, which also exhibited 35% lethality at a concentration of 1000 μg/mL, while the other fractions were not toxic.
Article Abstract
Steud. is distributed in Central and South America, commonly named as 'salsaparilha' or 'japicanga'. In the present work, the chemical composition was determined, antioxidant and cytotoxic effects were evaluated for the ethanol extract (EE) and fractions from leaves. Fatty acid esters and phytol were characterised in the hexane (HEX) fraction. -glycosylated flavonols and flavones, caffeic acid derivatives, and steroidal saponins were annotated for EE, and dichloromethane (DCM), ethyl acetate (AC), and hydroethanol (HE) fractions. The samples contain flavonoids and phenolic compounds, and the AC fraction displayed the biggest concentration of these substances. Antioxidant potential was observed in all samples, being especially pronounced in the AC fraction by DPPH and FRAP assays, with IC values of 8.18 and 2.35 µg/mL, respectively. AC and HEX fractions showed 35% and 5% lethality at 1000 μg/mL, in the assay, and the other samples did not show a toxic effect.
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| http://dx.doi.org/10.1080/14786419.2024.2324375 | DOI Listing |
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