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Giving birth after fertility-sparing treatment for primary leiomyosarcoma of the fallopian tube. | LitMetric

Giving birth after fertility-sparing treatment for primary leiomyosarcoma of the fallopian tube.

J Obstet Gynaecol Res

Department of Obstetrics and Gynecology, Shanghai East Hospital, School of Medicine, Tongji University, Shanghai, China.

Published: June 2024

AI Article Synopsis

  • Primary leiomyosarcoma of the fallopian tube (PLFT) is a rare cancer that's been documented mainly through individual case reports, with no previous fertility-sparing treatments recorded.
  • A 24-year-old woman diagnosed with stage IC1 PLFT underwent a laparoscopic procedure to remove her affected fallopian tube while preserving her fertility, followed by chemotherapy.
  • Remarkably, the patient conceived naturally and gave birth to a healthy baby 27 months later, marking this as the first reported success in preserving fertility in young women with PLFT.

Article Abstract

Primary leiomyosarcoma of the fallopian tube (PLFT) is an extremely rare gynecological malignancy that has only been described in case reports. Fertility-sparing treatment for PLFT has not been reported previously. A 24-year-old nulligravida woman was diagnosed with stage IC1 PLFT in the right fallopian tube after experiencing right lower quadrant pain for 2 weeks. She underwent laparoscopic right salpingectomy to preserve fertility followed by adjuvant chemotherapy with gemcitabine/docetaxel. She subsequently became pregnant spontaneously, delivering a term baby 27 months after treatment. This appears to be the only report of the use of fertility-preserving treatment for PLFT. The success of the treatment provides valuable information on the preservation of fertility in young women with PLFT.

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Source
http://dx.doi.org/10.1111/jog.15919DOI Listing

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