Glutathione (GSH) is a potent antioxidant, fragrance, and anti-browning agent in the field of food chemistry. The accurate GSH evaluation in food and vegetables is critical for instructing the right supplementation of GSH in body. However, most reported GSH fluorescent probes were utilized for the biological imaging. In this study, a new probe DCYP-GSH was developed by coupling of benzopyranonitrile as signal reporter to N-methylpyridine through C = C bond as binding site. Notably, a significant increase in fluorescence intensity and a λ red-shift of DCYP-GSH in electron spectra were found as a result of the response to GSH. Quantitative detection of GSH in water and milk samples were achieved using probe DCYP-GSH. The development of DCYP-GSH was anticipated to provide an effective toolkit for food safe evaluation.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.saa.2024.124085 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Simulation of Antral Conditions for Estimating Drug Apparent Equilibrium Solubility after a High-Calorie, High-Fat Meal.
Mol Pharm
January 2025
Department of Pharmacy, National and Kapodistrian University of Athens, Zografou 15771, Greece.
The simulation of antral conditions for estimating drug apparent equilibrium solubility after a high-calorie, high-fat meal is challenging. In this study, (1) we measured the apparent equilibrium solubility of two model lipophilic drugs, ketoconazole and danazol, in antral aspirates collected at various time points after a minced high-calorie, high-fat meal and a glass of water 30 min after initiation of meal administration, and we designated one point estimate for ketoconazole and one point estimate for danazol; (2) we evaluated the usefulness of FeSSGF-V2 and FEDGAS pH = 3 in reproducing the two point estimates; (3) we evaluated potential compositions of FeSSGF-V3 that simulate the pH, the buffer capacity toward both less acidic and more acidic values, and the antral lipid and protein contents with easily accessible, commercially available products, and (4) we identified the most useful composition of FeSSGF-V3 for reproducing the two point estimates. For both model drugs, apparent solubility in FeSSGF-V2 and in FEDGAS pH 3 deviated substantially from the corresponding point estimate.
View Article and Find Full Text PDFChanges in hematological and hematochemical parameters in lactating dairy sheep according to different pasture management and heat stress risk: A longitudinal study.
Vet Anim Sci
March 2025
Department of Agriculture, Food and Environment, University of Pisa, 56124 Pisa, Italy.
Sheep in Italy are exposed to heat stress (HS) for several months, increasing the risk of HS-related problems such as the decrease in growth, reproductive performance, milk quantity and quality and natural immunity. This study aimed to assess changes in hematological and biochemical parameters in dairy sheep from three different farms with varying pasture management: A (no water or shade), B (water but no shade), and C (both water and shade). From March to June, when HS risk is high, monthly blood samples (T1-T4) were collected from 20 sheep per farm (total n = 60).
View Article and Find Full Text PDFProtective effects of tiger milk mushroom extract (xLr®) against UVB irradiation in DAF-16 anti-oxidant regulation.
J Tradit Complement Med
January 2025
Immunomodulation of Natural Products Research Unit, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok 10330, Thailand.
Background And Aim: A critical causative factor of oxidative stress and inflammation leading to several skin complications is ultraviolet-B (UVB) irradiation. (LR), or tiger milk mushroom, is native to Southeast Asia. Cold water extract of an LR cultivar, TM02® (xLr®) is a promising anti-oxidant and anti-inflammatory source.
View Article and Find Full Text PDFBovine lactopontin promotes bone development in growing rats by altering the composition of intestinal flora and bile acid metabolism.
Food Funct
January 2025
School of Food Science and Technology, Jiangnan University, Wuxi, Jiangsu 214122, China.
Lactopontin (LPN) is an important milk protein with the potential to improve bone health; however, its specific effects have not been determined. This study aims to investigate the effects of LPN on early bone growth and development. 3 week-old SD rats ( = 32) were assigned to the control group, whey protein concentration (WPC) group, LPN-L (low-dose LPN) group, and LPN-H (high-dose LPN) group, with intragastric administration of deionized water, 65.
View Article and Find Full Text PDFAssociation of tea consumption with all-cause/cardiovascular disease mortality in the chronic kidney disease population: an assessment of participation in the national cohort.
Ren Fail
December 2025
State Key Laboratory of Traditional Chinese Medicine Syndrome, The First Affiliated Hospital, Guangzhou University of Chinese Medicine, Guangzhou, China.
Background: While there are numerous benefits to tea consumption, its long-term impact on patients with chronic kidney disease (CKD) remains unclear.
Method: Our analysis included 17,575 individuals with CKD from an initial 45,019 participants in the National Health and Nutrition Examination Survey (NHANES) (1999-2018). Individuals with extreme dietary habits, pregnancy, or non-CKD conditions were excluded.
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!