AI Article Synopsis
- Kolmioviridae is a family of negative-sense RNA viruses with circular genomes, found in various animals including mammals and birds.
- They can cause significant diseases, such as severe hepatitis in humans, particularly in the case of deltaviruses.
- Kolmiovirids rely on unrelated helper viruses for their envelopes and require specific cellular machinery for replication, including host DNA-directed RNA polymerase II.
Article Abstract
is a family for negative-sense RNA viruses with circular, viroid-like genomes of about 1.5-1.7 kb that are maintained in mammals, amphibians, birds, fish, insects and reptiles. Deltaviruses, for instance, can cause severe hepatitis in humans. Kolmiovirids encode delta antigen (DAg) and replicate using host-cell DNA-directed RNA polymerase II and ribozymes encoded in their genome and antigenome. They require evolutionary unrelated helper viruses to provide envelopes and incorporate helper virus proteins for infectious particle formation. This is a summary of the International Committee on Taxonomy of Viruses (ICTV) Report on the family , which is available at ictv.global/report/kolmioviridae.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11145878 | PMC |
| http://dx.doi.org/10.1099/jgv.0.001963 | DOI Listing |
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