Correction for 'Post-synthetic molecular modifications based on Schiff base condensation reactions for designing functional paddlewheel diruthenium(II,II) complexes' by Chisa Itoh , , 2024, , 444-448.
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Aminoglycoside tolerance in engages translational reprogramming associated with queuosine tRNA modification.
Elife
January 2025
Institut Pasteur, Université Paris Cité, Unité Plasticité du Génome Bactérien, Paris, France.
Tgt is the enzyme modifying the guanine (G) in tRNAs with GUN anticodon to queuosine (Q). is required for optimal growth of in the presence of sub-lethal aminoglycoside concentrations. We further explored here the role of the Q34 in the efficiency of codon decoding upon tobramycin exposure.
View Article and Find Full Text PDFThermal Actuators Relying on Elastomer-Dispersed Liquid Crystals: From Imines with Supramolecular Chirality and Ferroelectricity to Soft Robots.
ACS Appl Mater Interfaces
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Department of Inorganic Polymers, "Petru Poni" Institute of Macromolecular Chemistry, Aleea Gr. Ghica Voda 41A, 700487 Iasi, Romania.
The locomotion of various organisms relies on the alternated elongation-contraction of their muscles or bodies. Such biomimicry can offer a promising approach to developing soft robotic devices with improved mobility and efficiency. Most strategies to mimic such motions rely on reversible size modifications of some materials upon exposure to external stimuli.
View Article and Find Full Text PDFDetailed Characterization of the Conversion of Hardwood and Softwood Lignin by a Brown-Rot Basidiomycete.
Biomacromolecules
January 2025
Faculty of Chemistry, Biotechnology, and Food Science, Norwegian University of Life Sciences (NMBU), P.O. Box 5003, Ås 1433, Norway.
Wood-degrading brown-rot fungi primarily target carbohydrates, leaving the lignin modified and potentially valuable for valorization. Here, we report a comprehensive comparison of how degrades hardwood and softwood, which have fundamentally different lignin structures. By harnessing the latest advancements in analytical methodologies, we show that removes more lignin from wood (up to 36%) than previously reported.
View Article and Find Full Text PDFIntroductory Analysis and Validation of CUT&RUN Sequencing Data.
J Vis Exp
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Department of Epigenetics and Molecular Carcinogenesis, University of Texas MD Anderson Cancer Center; Department of Gynecologic Oncology and Reproductive Medicine, University of Texas MD Anderson Cancer Center;
The CUT&RUN technique facilitates detection of protein-DNA interactions across the genome. Typical applications of CUT&RUN include profiling changes in histone tail modifications or mapping transcription factor chromatin occupancy. Widespread adoption of CUT&RUN is driven, in part, by technical advantages over conventional ChIP-seq that include lower cell input requirements, lower sequencing depth requirements, and increased sensitivity with reduced background signal due to a lack of cross-linking agents that otherwise mask antibody epitopes.
View Article and Find Full Text PDFGene expression and DNA methylation changes in response to hypoxia in toxicant-adapted Atlantic killifish (Fundulus heteroclitus).
Biol Open
January 2025
Biology Department, Woods Hole Oceanographic Institution, Woods Hole, MA 02543,USA.
Coastal fish populations are threatened by multiple anthropogenic impacts, including the accumulation of industrial contaminants and the increasing frequency of hypoxia. Some populations of the Atlantic killifish (Fundulus heteroclitus), like those in New Bedford Harbor (NBH), Massachusetts, USA, have evolved a resistance to dioxin-like polychlorinated biphenyls (PCBs) that may influence their ability to cope with secondary stressors. To address this question, we compared hepatic gene expression and DNA methylation patterns in response to mild or severe hypoxia in killifish from NBH and Scorton Creek (SC), a reference population from a relatively pristine environment.
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