Load growth puts pressure on existing electric infrastructure and impacts on the system's performance parameters which may necessitate network expansion. Conventionally, electric network expansion is done by building new substations or reinforcing the existing ones with new transformers and upgrading the network feeders. However, optimal allocation of combined heat and power distributed generators (CHP-DGs) on distribution networks (DNs) can be adopted for network expansion planning problem. Optimal DG allocation is an optimisation problem which requires an efficient optimisation approach. In this paper, an improved particle swarm optimisation (IPSO) based on weighted randomised acceleration coefficient and adaptive inertia weight is proposed for optimal DG allocation problem. The considered CHP-DGs include internal combustion engine (ICE) and fuel cells (FCs) powered by biogas obtained from anaerobic digestion of food wastes. The proposed IPSO is tested on IEEE 69 bus radial distribution network under single and multi-objectives considering constant and mixed seasonal voltage-dependent load models. Some of the key findings show that integrating ICE-based CHP-DGs operating at optimal power factor in winter day mixed voltage dependent load in base year achieves 97.63 % active power loss reduction in comparison to 77.14 % loss reduction for unity power factor operating FC-based CHP-DG. Economic and environmental evaluation indicate that FC-based CHP-DG records a net present value of over 29.29 million $, levelised cost of energy of 0.0493 $/kWh and zero pollutant emission in comparison with 28.40 million $, 0.0501 $/kWh and 0.2817 million kg pollutant emission for ICE-based CHP-DG over the planning horizon. In comparison with the standard PSO, the proposed IPSO performs better in terms of solution quality, convergence speed and statistical results.
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http://dx.doi.org/10.1016/j.heliyon.2024.e26254 | DOI Listing |
Bioinformatics
January 2025
School of Computer Science and engineering, Central South University, Changsha, 410083, China.
Motivation: T-cell receptors (TCRs) elicit and mediate the adaptive immune response by recognizing antigenic peptides, a process pivotal for cancer immunotherapy, vaccine design, and autoimmune disease management. Understanding the intricate binding patterns between TCRs and peptides is critical for advancing these clinical applications. While several computational tools have been developed, they neglect the directional semantics inherent in sequence data, which are essential for accurately characterizing TCR-peptide interactions.
View Article and Find Full Text PDFAm J Transplant
January 2025
Division of Nephrology, Department of Medicine, Vagelos College of Physicians & Surgeons, Columbia University, New York, NY; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY.
There is substantial variation in access to transplantation across the United States that is not entirely explained by the availability of donor organs. Barriers to transplantation and variation in care among patients with end-stage organ disease exist prior to patients' placement on a transplant waiting list as well as following waitlist placement. However, there are currently no national data available to examine rates and variations in key care processes related to pre-listing, including transplant referral, evaluation, or candidate selection.
View Article and Find Full Text PDFEnviron Res
January 2025
College of Environment, Hohai University, Nanjing 210024, China.
The expansion of aquaculture areas has encroached upon vast areas of coastal wetlands and introduced excessive nitrogen inputs, disrupting microbial communities and contributing to various environmental issues. However, investigations on how aquaculture affects microbial communities and nitrogen metabolism mechanisms in coastal tidal flats remain scarce. Hence, we explored the composition, diversity, and assembly processes of nitrogen-cycling (N-cycling) microbial communities in tidal flats in Jiangsu using metagenomic assembly methods.
View Article and Find Full Text PDFActa Crystallogr B Struct Sci Cryst Eng Mater
February 2025
CSIRO Division of Mineral Products, Port Melbourne, Victoria, Australia.
The crystallographic phase change from tetragonal litharge (α-PbO; P4/nmm) to orthorhombic massicot (β-PbO; Pbcm) has been studied by full-matrix Rietveld analysis of high-temperature neutron powder diffraction data collected in equal steps from ambient temperature up to 925 K and back down to 350 K. The phase transformation takes place between 850 and 925 K, with the coexisting phases having equal abundance by weight at 885 K. The product massicot remains metastable on cooling to near ambient temperature.
View Article and Find Full Text PDFUnlabelled: Transparent and accurate reporting in early phase dose-finding (EPDF) clinical trials is crucial for informing subsequent larger trials. The SPIRIT statement, designed for trial protocol content, does not adequately cover the distinctive features of EPDF trials. Recent findings indicate that the protocol contents in past EPDF trials frequently lacked completeness and clarity.
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