Background: Observational studies and animal experiments suggested potential relevance between gut microbiota (GM) and cervical cancer (CC), but the relevance of this association remains to be clarified.
Methods: We performed a two-sample bidirectional Mendelian randomization (MR) analysis to explore whether there was a causal correlation between GM and CC, and the direction of causality.
Results: In primary outcomes, we found that a higher abundance of and predicted higher risk of CC, and a higher abundance of and predicted lower risk of CC. During verifiable outcomes, we found that a higher abundance of and predicted a higher risk of CC, and a higher abundance of and predicted a lower risk of CC, and vice versa.
Conclusion: Our study implied a mutual causality between GM and CC, which provided a novel concept for the occurrence and development of CC, and might promote future functional or clinical analysis.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10901247 | PMC |
| http://dx.doi.org/10.3389/fmicb.2024.1336101 | DOI Listing |
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