Natural language processing for defining linguistic features in schizophrenia: A sample from Turkish speakers.

Schizophr Res

Department of Psychology, National Magnetic Resonance Research Center (UMRAM) & Aysel Sabuncu Brain Research Center, Bilkent University, Bilkent, 06800 Ankara, Turkey; 1(st) Department of Psychiatry, National and Kapodistrian University of Athens, Athens, Greece; Department of Psychiatry, Icahn School of Medicine at Mount Sinai, New York, USA. Electronic address:

Published: April 2024

Natural language processing (NLP) provides fast and accurate extraction of features related to the language of schizophrenia. We utilized NLP methods to test the hypothesis that schizophrenia is associated with altered linguistic features in Turkish, a non-Indo-European language, compared to controls. We also explored whether these possible altered linguistic features were language-dependent or -independent. We extracted and compared speech in schizophrenia (SZ, N = 38) and healthy well-matched control (HC, N = 38) participants using NLP. The analysis was conducted in two parts. In the first one, mean sentence length, total completed words, moving average type-token ratio to measure the lexical diversity, and first-person singular pronoun usage were calculated. In the second one, we used parts-of-speech tagging (POS) and Word2Vec in schizophrenia and control. We found that SZ had lower mean sentence length and moving average type-token ratio but higher use of first-person singular pronoun. All these significant results were correlated with the Thought and Language Disorder Scale score. The POS approach demonstrated that SZ used fewer coordinating conjunctions. Our methodology using Word2Vec detected that SZ had higher semantic similarity than HC and K-Means could differentiate between SZ and HC into two distinct groups with high accuracy, 86.84 %. Our findings showed that altered linguistic features in SZ are mostly language-independent. They are promising to describe language patterns in schizophrenia which proposes that NLP measurements may allow for rapid and objective measurements of linguistic features.

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http://dx.doi.org/10.1016/j.schres.2024.02.026DOI Listing

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