The timely detection of abnormal electrocardiogram (ECG) signals is vital for preventing heart disease. However, traditional automated cardiology diagnostic methods have the limitation of being unable to simultaneously identify multiple diseases in a segment of ECG signals, and do not consider the potential correlations between the 12-lead ECG signals. To address these issues, this paper presents a novel network architecture, denoted as Branched Convolution and Channel Fusion Network (BCCF-Net), designed for the multi-label diagnosis of ECG cardiology to achieve simultaneous identification of multiple diseases. Among them, the BCCF-Net incorporates the Channel-wise Recurrent Fusion (CRF) network, which is designed to enhance the ability to explore potential correlation information between 12 leads. Furthermore, the utilization of the squeeze and excitation (SE) attention mechanism maximizes the potential of the convolutional neural network (CNN). In order to efficiently capture complex patterns in space and time across various scales, the multi branch convolution (MBC) module has been developed. Through extensive experiments on two public datasets with seven subtasks, the efficacy and robustness of the proposed ECG multi-label classification framework have been comprehensively evaluated. The results demonstrate the superior performance of the BCCF-Net compared to other state-of-the-art algorithms. The developed framework holds practical application in clinical settings, allowing for the refined diagnosis of cardiac arrhythmias through ECG signal analysis.
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http://dx.doi.org/10.1016/j.compbiomed.2024.108210 | DOI Listing |
Alzheimers Dement
December 2024
Cranfield University, Bedford, Bedfordshire, United Kingdom.
Background: Distress and agitation are predictors of entry into long-term care and health inequalities (Schulz et al., 2004, Weir et al., 2022).
View Article and Find Full Text PDFBackground: VG-3927 is a highly potent, selective, brain penetrant, oral small molecule TREM2 agonist that is currently under development for the treatment of Alzheimer's disease (AD). TREM2, a receptor expressed on microglia in the brain is critical to microglial function in health and in disease. Among microglia-associated AD risk genes, partial loss-of-function variants of TREM2 confer 2-3 fold increase in risk for developing AD, motivating efforts to identify pharmacological agonists targeting TREM2 as a therapeutic option.
View Article and Find Full Text PDFBiomed Eng Lett
January 2025
Department of Biomedical Engineering, Yonsei University College of Software and Digital Healthcare Convergence, Wonju-si, Gangwon-do 26493 Republic of Korea.
The rise in individuals living alone in ageing societies raises concerns about social isolation and associated health risks, notably lonely deaths among the elderly. Traditional electrocardiogram (ECG) monitoring systems, reliant on intrusive and potentially irritating electrodes, pose practical challenges. This study examines the efficacy of conductive textile electrodes (CTEs) vis-á-vis conventional electrodes (CEs) in ECG monitoring, along with the effect of electrode positioning.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
School of Automation Engineering, University of Electronic Science and Technology of China, Chengdu 610054, China.
Vertical organic electrochemical transistors (vOECTs) have received widespread attention in bioelectronics, wearable, and neuromorphic electronics due to their high transconductance (), low driving voltage, and biocompatibility. As key parameters of vOECTs, and switching speed (or transient time, τ) are vital for achieving satisfying performance in various practical applications. Here we employ vOECTs with varying top electrode widths for effective and switching speed modulation.
View Article and Find Full Text PDFBMC Cardiovasc Disord
January 2025
Cardio/Endo-metabolic and Microbiome Research Unit, Department of Physiology, College of Medicine and Health Sciences, Afe Babalola University, Ado-Ekiti, 360101, Nigeria.
Background: Hypertension is a major cause of cardiac dysfunction. The earliest manifestation is left ventricular remodeling/hypertrophy. The occurrence of adverse cardiac remodeling and outcomes occurs irrespective of age in blacks.
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