AI Article Synopsis

  • There is limited research on how hepatitis C (HCV) affects pregnancy outcomes, leading to conflicting information about its risks.
  • A study using the SET-NET data showed that 89% of the 1418 infants studied were born to individuals who reported substance use during pregnancy, highlighting a concerning link.
  • Key findings revealed that 20% of infants were born preterm, 13% were small-for-gestational age, and a significant 34% of term infants needed intensive care, suggesting a need to review current HCV screening recommendations in pregnant individuals.

Article Abstract

Introduction: There are limited and conflicting data regarding the impact of hepatitis C in pregnancy on adverse birth outcomes.

Methods: Using the Surveillance for Emerging Threats to Pregnant People and Infants Network (SET-NET), a large surveillance cohort, we describe birth outcomes among a cohort of people with HCV in pregnancy in total and by reported substance use.

Results: Among 1418 infants, 89% were born to people with reported substance use during pregnancy. The proportion born preterm was 20%, 13% were small-for-gestational age and 34% of term infants required intensive care.

Conclusions: Assessments of recent changes to recommendations for HCV screening in pregnancy should evaluate the impact on maternal access to care for both HCV treatment as well as comorbidities such as substance use disorder which may contribute to adverse birth outcomes.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC11060891PMC
http://dx.doi.org/10.1007/s10995-024-03917-3DOI Listing

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