Cross-species real time detection of trends in pupil size fluctuation.

bioRxiv

Section on Functional Imaging Methods, Laboratory of Brain and Cognition, National Institute of Mental Health (NIMH), National Institutes of Health (NIH), Bethesda, Maryland (MD), United States of America (USA).

Published: August 2024

Pupillometry is a popular method because pupil size is easily measured, sensitive to central neural activity, and associated with behavior, cognition, emotion, and perception. Currently, there is no method for online monitoring phases of pupil size fluctuation. We introduce - an open source software that automatically detects trends in pupil size in real time, enabling novel implementations of real time pupillometry towards achieving numerous research and translational goals. We validated the performance of rtPupilPhase on human, rodent, and monkey pupil data and propose future applications of real time pupillometry.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10896349PMC
http://dx.doi.org/10.1101/2024.02.12.579393DOI Listing

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