AI Article Synopsis
- - Fixed drug eruption (FDE) is a skin reaction that happens again in the same places when a person is exposed to the same drug again.
- - FDE typically appears as one or more purple patches on the skin, often with darkening due to inflammation.
- - An interesting case involved a generalized FDE caused by cefepime, which improved after stopping the drug and using antihistamines and topical steroids.
Article Abstract
Fixed drug eruption (FDE) is a cutaneous reaction that characteristically recurs in the same locations upon re-exposure to the offending drug(s). The typical presentation of FDEs is single or multiple violaceous plaques with hyperpigmentation due to inflammation. The causative agents for FDEs include antibiotics, nonsteroidal anti-inflammatory drugs (NSAIDs), acetaminophen, barbiturates, and anticonvulsants. We present an interesting case of a generalized fixed drug eruption secondary to cefepime that resolved with the cessation of the offending drug and the institution of antihistamines and topical steroids.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10894754 | PMC |
| http://dx.doi.org/10.7759/cureus.53011 | DOI Listing |
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