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Leveraging international stakeholders' experiences with oral PrEP costs to accelerate implementation of the monthly dapivirine vaginal ring: A qualitative study.
Health Res Policy Syst
November 2024
Department of Epidemiology, Columbia University Mailman School of Public Health, 622 West 168th Street, 8th Floor, New York, NY, 10032, United States of America.
Background: Costing and financing systematic implementation are recognized barriers to human immunodeficiency virus (HIV) prevention. In the absence of empiric implementation and economic data, perspectives from international stakeholders involved in developing and supporting daily oral pre-exposure prophylaxis (PrEP) policy, and programs can provide critical insights for developing costed plans to support and accelerate the rollout of novel long-acting PrEP (LA-PrEP) methods, such as the monthly dapivirine vaginal ring (PrEP ring).
Methods: We interviewed stakeholders from purposively selected international organizations about anticipated PrEP-ring implementation costs, evidence gaps and key process steps for developing a costed rollout plan template (CRPT).
Addressing Hypertension and Diabetes through Community-Engaged Systems (ANDES) in Puno, Peru: rationale and study protocol for a hybrid type 2 effectiveness and implementation randomized controlled trial.
Trials
November 2024
Facultad de Salud Pública y Administración, Universidad Peruana Cayetano Heredia, Lima, Peru.
Article Synopsis
- - This study focuses on tackling hypertension in Peru through a hybrid research design testing a community health worker (CHW)-led program, aiming to improve blood pressure control within the national primary care system in Puno.
- - A total of 1068 adults with hypertension will be recruited and randomly assigned to either usual care or a 12-month intervention, which includes home-based monitoring, medication support, and lifestyle counseling.
- - The trial will evaluate clinical effectiveness (like changes in blood pressure) and implementation outcomes (such as program acceptance and cost-effectiveness), providing valuable insights for future health strategies in Peru and similar low- to middle-income countries (LMICs).
Background: In Vietnam, there is a paucity of health-related quality of life (HRQoL) research on people with depression as well as a lack of evidence on supported self-management (SSM) intervention for depression on HRQoL. This study aimed to compare the HRQoL of people with depression and age-matched people in the Vietnamese population, evaluate the effects of Tele-SSM intervention on HRQoL, and examine the association between the changes in HRQoL score and mental health well-being (depression, anxiety, and stress).
Methods: This study was a pre- and post-study involving Vietnamese adults aged 18-64 who had depression symptoms (score ≥ 5 points in the PHQ-9).
Evaluating a multifaceted implementation strategy and package of evidence-based interventions based on WHO PEN for people living with HIV and cardiometabolic conditions in Lusaka, Zambia: protocol for the TASKPEN hybrid effectiveness-implementation stepped wedge cluster randomized trial.
Implement Sci Commun
June 2024
Centre for Infectious Disease Research in Zambia (CIDRZ), Lusaka, Zambia.
Article Synopsis
- Non-communicable diseases (NCDs) are a rising threat in low- and middle-income countries, especially in sub-Saharan Africa, where health systems struggle to meet the challenge, particularly among people living with HIV (PLHIV).
- The "TASKPEN" initiative has been developed to provide a targeted strategy for addressing hypertension, diabetes, and dyslipidemia in Zambia, utilizing lessons from HIV care to create an integrated approach involving task-shifting and leveraging existing health platforms.
- A cluster randomized trial will be conducted in Lusaka to evaluate TASKPEN's impact on managing both HIV and cardiometabolic diseases, measuring clinical outcomes, quality of life, and cost-effectiveness through a variety of research methods
A scoping review of the literature on the application and usefulness of the Problem Management Plus (PM+) intervention around the world.
BJPsych Open
April 2024
Institute for Human Development, Aga Khan University, Kenya; Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute (KEMRI), Kilifi, Kenya; and Department of Psychiatry, University of Oxford, UK.
Background: Given the high rates of common mental disorders and limited resources, task-shifting psychosocial interventions are needed to provide adequate care. One such intervention developed by the World Health Organization is Problem Management Plus (PM+).
Aims: This review maps the evidence regarding the extent of application and usefulness of the PM+ intervention, i.
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