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Using the Key Characteristics Framework to Unlock the Mysteries of Aryl Hydrocarbon Receptor-Mediated Effects on the Immune System.
Annu Rev Immunol
January 2025
3Department of Environmental Medicine and Department of Microbiology and Immunology, University of Rochester, Rochester, New York, USA; email:
Initially discovered for its role mediating the deleterious effects of environmental contaminants, the aryl hydrocarbon receptor (AHR) is now known to be a crucial regulator of the immune system. The expanding list of AHR ligands includes synthetic and naturally derived molecules spanning pollutants, phytochemicals, pharmaceuticals, and substances derived from amino acids and microorganisms. The consequences of engaging AHR vary, depending on factors such as the AHR ligand, cell type, immune challenge, developmental state, dose, and timing of exposure relative to the immune stimulus.
View Article and Find Full Text PDFEvaluating Online and Offline Health Information With the Patient Education Materials Assessment Tool: Protocol for a Systematic Review.
JMIR Res Protoc
January 2025
University hospital Medical Information Network (UMIN) Center, The University of Tokyo Hospital, Tokyo, Japan.
Background: The Patient Education Materials Assessment Tool (PEMAT) is a reliable and validated instrument for assessing the understandability and actionability of patient education materials. It has been applied across diverse cultural and linguistic contexts, enabling cross-field and cross-national material quality comparisons. Accumulated evidence from studies using the PEMAT over the past decade underscores its potential impact on patient and public action.
View Article and Find Full Text PDFClinical simulation training for first responders in pediatric emergencies with family interaction: a scoping review.
Rev Bras Enferm
January 2025
Universidade Federal de Mato Grosso do Sul. Campo Grande, Mato Grosso do Sul, Brazil.
Objective: To map studies on clinical simulation training directed at first responders during pediatric emergencies, focusing on interaction with families.
Methods: A scoping review based on the guidelines of the JBI Manual for Evidence Syntheses and reported according to the PRISMA-ScR checklist, covering eight databases and gray literature, without time or language restrictions.
Results: The ten selected studies indicated that most publications were from the United States.
Nurses' perspectives on the use of telemonitoring in the management of people with diabetes and hypertension.
Rev Bras Enferm
January 2025
Universidade Estadual de Maringá. Maringá, Paraná, Brazil.
Objectives: to understand the perspective of nurses on the use of telemonitoring in the management of people with type 2 diabetes mellitus and arterial hypertension in primary care.
Methods: this qualitative research involved sixteen nurses from eight municipalities in Paraná. Data were collected between November 2022 and January 2023 through inperson or remote interviews, which were audio-recorded and subjected to content analysis.
The influence of social networks on finding and selecting healthcare professionals.
Braz Oral Res
January 2025
Universidade Estadual de Campinas - Unicamp, School of Applied Sciences, Campinas, SP, Brazil.
Social networks consist of a group of individuals connected by family, work, or other interests and facilitated by an online structure or platform. They are also a relatively recent and widely used marketing phenomenon that is constantly evolving. The healthcare field includes professions such as social work, biology, biomedicine, physical education, nursing, pharmacy, physiotherapy, speech therapy, medicine, veterinary medicine, nutrition, dentistry, psychology, and occupational therapy.
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