Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10884661 | PMC |
| http://dx.doi.org/10.7861/fhj.10-3-s57 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Optimal placement of high-channel visual prostheses in human retinotopic visual cortex.
J Neural Eng
January 2025
Faculty of Psychology, University of Maastricht, P.O. Box 616, 6200 MD Maastricht, The Netherlands, Maastricht, 6211 LK, NETHERLANDS.
Recent strides in neurotechnology show potential to restore vision in individuals afflicted with blindness due to early visual pathway damage. As neuroprostheses mature and become available to a larger population, manual placement and evaluation of electrode designs becomes costly and impractical. An automatic method to optimize the implantation process of electrode arrays at large-scale is currently lacking.
View Article and Find Full Text PDFLarge library docking of tangible molecules has revealed potent ligands across many targets. While make-on-demand libraries now exceed 75 billion enumerated molecules, their synthetic routes are dominated by a few reaction types, reducing diversity and inevitably leaving many interesting bioactive-like chemotypes unexplored. Here, we investigate the large-scale enumeration and targeted docking of isoquinuclidines.
View Article and Find Full Text PDFDigital channel-enabled distributed force decoding via small datasets for hand-centric interactions.
Sci Adv
January 2025
Department of Electronic and Computer Engineering, Hong Kong University of Science and Technology, Hong Kong, 999077, China.
Tactile interfaces are essential for enhancing human-machine interactions, yet achieving large-scale, precise distributed force sensing remains challenging due to signal coupling and inefficient data processing. Inspired by the spiral structure of and the processing principles of neuronal systems, this study presents a digital channel-enabled distributed force decoding strategy, resulting in a phygital tactile sensing system named PhyTac. This innovative system effectively prevents marker overlap and accurately identifies multipoint stimuli up to 368 regions from coupled signals.
View Article and Find Full Text PDFIdentification of novel triazolylquinoxaline-based metal complexes supported by experimental and virtual screenings.
Dalton Trans
January 2025
Institute of Biological and Chemical Systems (IBCS-FMS), Karlsruhe Institute of Technology, Kaiserstraße 12, 76131 Karlsruhe, Germany.
The formation of novel complexes from so far non-investigated ligands and different metal centers is important for the development of new functional materials such as (photo)catalysts or biologically active compounds. Still, promising strategies to quickly and systematically investigate the complexation behavior of selected ligands are rare. We developed an NMR-based screening approach to monitor changes within reaction mixtures containing metals and ligands on a small scale a simple but reliable protocol.
View Article and Find Full Text PDFVirtual Human Retina: Simulating Neural Signalling, Degeneration, and Responses to Electrical Stimulation.
Brain Stimul
January 2025
Graduate School of Biomedical Engineering, UNSW, Sydney, NSW 2052, Australia; Tyree Foundation Institute of Health Engineering (IHealthE), UNSW, Sydney, NSW 2052, Australia. Electronic address:
Introduction: Current brain-based visual prostheses pose significant challenges impeding adoption such as the necessarily complex surgeries and occurrence of more substantial side effects due to the sensitivity of the brain. This has led to much effort toward vision restoration being focused on the more approachable part of the brain - the retina. Here we introduce a novel, parameterized simulation platform that enables study of human retinal degeneration and optimization of stimulation strategies.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!