Methicillin-resistant meningitis is commonly associated with surgical procedures that closely interact with the central nervous system; however, hematogenous spread via bacteremia is rarely reported. Here, we present a case of methicillin-resistant meningitis as a complication of a diabetic foot infection that disseminated into a bloodstream infection causing infective endocarditis, discitis, vertebral osteomyelitis, and meningitis that was successfully treated with intravenous daptomycin and rifampin.
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http://dx.doi.org/10.7759/cureus.52969 | DOI Listing |
ACS Omega
December 2024
Faculty of Biology-Biotechnology, University of Science, Vietnam National University Ho Chi Minh City, 227 Nguyen Van Cu, District 5, Ho Chi Minh City 749000, Vietnam.
is a human pathogen responsible for a variety of diseases, from skin, soft tissue, and lung infections to severe cases such as meningitis, infective endocarditis, and bacteremia. The high level of antibiotic resistance in these pathogens, exemplified by methicillin-resistant (MRSA), necessitates the development of effective antibiotics. Thus, this work introduced the chemical synthesis of ethyl 3,5-dibromoorsellinate, a derivative of ethyl orsellinate from the lichen mycobiont of , and its effectiveness against MRSA was assessed.
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October 2024
Internal Medicine, Jackson Memorial Hospital, Miami, USA.
Orbital cellulitis is a serious infection that can lead to severe complications if not promptly diagnosed and treated. This case report describes an unusual presentation of bilateral orbital cellulitis in a previously healthy 29-year-old female, complicated by cerebral vein thrombosis and meningitis. The patient's young age and lack of significant medical history make this case particularly noteworthy.
View Article and Find Full Text PDFVaccines (Basel)
September 2024
Department of Biomedical Sciences, University of Pikeville, Pikeville, KY 41501, USA.
Cureus
September 2024
Department of Analytical and Toxicological Chemistry, Medical Academy, Lithuanian University of Health Sciences, Kaunas, LTU.
Background: Antimicrobial resistance is currently one of the most significant threats to medical science, necessitating the exploration of new antimicrobial agents. Methicillin-resistant (MRSA) can lead to various severe conditions such as endocarditis, meningitis, abscesses, and sepsis, and conventional antibiotics such as beta-lactams are ineffective for treating these diseases. Therefore, it is imperative to search for novel chemical substances with antimicrobial effects against MRSA.
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September 2024
Surgery, Montefiore Medical Center, Wakefield Campus, Bronx, USA.
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