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The goal of this work was the evaluation of the frequency of human CMV infection among the women, whose pregnancy ended in miscarriage, detection of active forms of infection and treatment before pregnancy. Virological and sero-immunological techniques were used. A total of 116 women who had miscarriages before the 28 week of pregnancy were submitted to the CMV test.
View Article and Find Full Text PDFThymus Polypeptide Preparation Tactivin Restores Learning and Memory in Thymectomied Rats.
Bull Exp Biol Med
September 2015
Laboratory of Molecular Immunology and Biochemistry, Research Institute of Physicochemical Medicine, Federal Medical-and-Biological Agency of Russia, Moscow, Russia.
We studied the effects of tactivin and splenic polypeptides on learning and memory of thymectomized animals. In 3-week rats, thymectomy blocked active avoidance conditioning. Injections of tactivin (0.
View Article and Find Full Text PDF[The impact of immunoactive drugs on passive avoidance response].
Vestn Ross Akad Med Nauk
February 2015
Aim: The objective of this project was to explore the influence of immunoactive drugs (tactivin, thymulin, and thymosin fraction 5) on the development of the passive avoidance conditioned reflex.
Materials And Methods: Two types of passive avoidance boxes were used--a regular two-chamber box and a modified three-chamber box, comprising a dark chamber in which rats were exposed to electrical shock, a safe dark chamber, and a light chamber in the center.
Results: The project has established that the memory trace persists longer under the influence of the immunoactive drugs in both models, which is consistent with the reference nootropic piracetam test results.
The effect of tactivin on analgesia induced by acute and chronic immobilization.
Dokl Biol Sci
September 2014
Faculty of Biology, Moscow State University, Moscow, 119992, Russia,
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