AI Article Synopsis

  • Drug reactions are a significant concern in anti-cancer therapies, with less common risks like toxic erythema linked to chemotherapy.
  • Patients undergoing cancer treatments have weakened immune systems, making them more prone to infections.
  • The text discusses a rare case where a patient's skin condition evolved into a severe reaction after starting treatment with bevacizumab and lorlatinib, leading to a combined skin infection.

Article Abstract

Drug reactions are a known risk in combined anti-cancer therapy. Less commonly recognized risks of chemotherapies and targeted immunotherapies include toxic erythema of chemotherapy reactions. With the immunosuppressive quality of cancer combined with anti-cancer treatments, patients are also susceptible to increased infection. We report a rare case of combined targeted anti-cancer treatment with bevacizumab and lorlatinib, and an associated transformation of an eczematous process into a toxic erythema of chemotherapy vasculitic eruption, with combined malignant intertrigo characteristics and superimposed infection following the initiation of bevacizumab.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10884723PMC
http://dx.doi.org/10.7759/cureus.52816DOI Listing

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