Dimensionality reduction plays a pivotal role in preparing high-dimensional data for classification and discrimination tasks by eliminating redundant features and enhancing the efficiency of classifiers. The effectiveness of a dimensionality reduction algorithm hinges on its numerical stability. When data projections are numerically stable, they lead to enhanced class separability in the lower-dimensional embedding, consequently yielding higher classification accuracy. This paper investigates the numerical attributes of dimensionality reduction and discriminant subspace learning, with a specific focus on Locality-Preserving Partial Least Squares Discriminant Analysis (LPPLS-DA). High-dimensional data frequently introduce singularity in the scatter matrices, posing a significant challenge. To tackle this issue, the paper explores two robust implementations of LPPLS-DA. These approaches not only optimize data projections but also capture more discriminative features, resulting in a marked improvement in classification accuracy. Empirical evidence supports these findings through numerical experiments conducted on synthetic and spectral datasets. The results demonstrate the superior performance of the proposed methods when compared to several state-of-the-art dimensionality reduction techniques in terms of both classification accuracy and dimension reduction.
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http://dx.doi.org/10.1016/j.heliyon.2024.e26157 | DOI Listing |
Eye (Lond)
January 2025
Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, Beihang University, Beijing, China.
Objectives: To use finite element (FE) modeling and in vivo optical coherence tomography (OCT) imaging to explore the effect of ciliary muscle traction on optic nerve head (ONH) deformation during accommodation.
Methods: We developed a FE model to mimic the ciliary muscle traction during accommodation, and varied the stiffness of the sclera, choroid, Bruch's membrane (BM), prelaminar neural tissue and lamina cribrosa (LC) to assess their effects on accommodation-induced ONH strains. To validate the FE model, OCT images of the right eyes' ONHs from 20 subjects (25 ± 1.
ChemSusChem
January 2025
Korea Institute of Energy Technology, Energy Engineering, 21 KENTECH-gil, 58330, Naju-si, KOREA, REPUBLIC OF.
Cu2O has attracted significant attention as a potential photocatalyst for CO2 reduction. However, its practical use is limited by rapid charge recombination, insufficient catalytic sites, and poor stability. In this study, we report a facile synthesis of Cu2O@BiOCl core-shell hybrids with well-defined shape of Cu2O and two-dimensional nanosheet structure of BiOCl.
View Article and Find Full Text PDFJ Orthop Surg Res
January 2025
Department of Orthopedics, Beijing Chaoyang Hospital, Capital Medical University, 8 Gongren Tiyuchang Nanlu, Chaoyang District, Beijing, 100020, China.
Background: Finite element analysis (FEA) could advance the understanding of fracture fixation and guide the choice of surgical treatment. This study aimed to compare two internal fixation methods in the treatment of displaced proximal humeral fracture (PHF) through FEA.
Methods: Three-dimensional FEA model based on the left shoulder joint of a 67-year-old female patient with PHFs and osteoporosis was adopted, in order to analyze the fixation effect and load stress distribution of internal fixation plates with open reduction and intramedullary nails without opening the fracture in the treatment of Neer III-VI PHF.
Phys Rev Lett
December 2024
Harish-Chandra Research Institute, A CI of Homi Bhabha National Institute, Chhatnag Road, Jhusi, Allahabad 211019, India.
Pump-probe response of the spin-orbit coupled Mott insulator Sr_{2}IrO_{4} reveals a rapid creation of low-energy optical weight and suppression of three-dimensional magnetic order on laser pumping. Postpump there is a quick reduction of the optical weight but a very slow recovery of the magnetic order-the difference is attributed to weak interlayer exchange in Sr_{2}IrO_{4} delaying the recovery of three-dimensional magnetic order. We suggest that the effect has a very different and more fundamental origin.
View Article and Find Full Text PDFAlzheimers Dement
December 2024
Queen Mary University of London, London, London, United Kingdom.
Background: Recent studies suggest the existence of distinct molecular subtypes within the AD patient cohort, characterized by distinct gene expression patterns in AD-relevant genes and pathways. Understanding these putative subtypes may prove pivotal to the greater understanding of AD pathology and developing targeted therapeutic interventions. This study aims to extend existing research by employing omics data modalities beyond gene expression, gathered from the ROSMAP and MSBB Alzheimer's studies.
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