AI Article Synopsis
- The study utilized UHPLC-Q-TOF-MS/MS to perform a qualitative analysis of the chemical constituents in Schizonepetae Spica.
- An Agilent poroshell 120 SB-C_(18) column was used for gradient elution with a specific mobile phase and set parameters for optimal results.
- A total of 97 compounds were identified, which included various categories like flavonoids, phenolic acids, and terpenoids, showcasing the method's ability to quickly and accurately identify the chemical components of the plant.
Article Abstract
The chemical constituents of Schizonepetae Spica were qualitatively analyzed by UHPLC-Q-TOF-MS/MS. An Agilent poroshell 120 SB-C_(18) column(3.0 mm×100 mm, 2.7 μm) was used for gradient elution with 0.1% formic acid water(A)-acetonitrile(B) solution as mobile phase at the flow rate of 0.4 mL·min~(-1) and column temperature of 45 ℃. The data were collected by scanning in positive and negative ion modes, and the compounds were identified by comparison of reference materials and PeakView software. Ninety-seven compounds were identified from Schizonepetae Spica, including 28 flavonoids, 23 phenolic acids, 23 fatty acids, 15 terpenoids, and 8 other compounds. The UHPLC-Q-TOF-MS/MS method established in this study can identify the chemical components of Schizonepetae Spica rapidly, accurately, and comprehensively, and provide a basis for the basic study of pharmacodynamic substances of Schizonepetae Spica.
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| http://dx.doi.org/10.19540/j.cnki.cjcmm.20230822.201 | DOI Listing |
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Article Synopsis
- The study utilized UHPLC-Q-TOF-MS/MS to perform a qualitative analysis of the chemical constituents in Schizonepetae Spica.
- An Agilent poroshell 120 SB-C_(18) column was used for gradient elution with a specific mobile phase and set parameters for optimal results.
- A total of 97 compounds were identified, which included various categories like flavonoids, phenolic acids, and terpenoids, showcasing the method's ability to quickly and accurately identify the chemical components of the plant.
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