Photosynthetic cryptophytes are ubiquitous protists that are major participants in the freshwater phytoplankton bloom at the onset of spring. Mortality due to change in environmental conditions and grazing have been recognized as key factors contributing to bloom collapse. In contrast, the role of viral outbreaks as factors terminating phytoplankton blooms remains unknown from freshwaters. Here, we isolated and characterized a cryptophyte virus contributing to the annual collapse of a natural cryptophyte spring bloom population. This viral isolate is also representative for a clade of abundant giant viruses (phylum Nucleocytoviricota) found in freshwaters all over the world.
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http://dx.doi.org/10.1093/ismejo/wrae029 | DOI Listing |
Sci Total Environ
January 2025
Cawthron Institute, 98 Halifax Street East, Nelson 7010, New Zealand. Electronic address:
In New Zealand, the frequency and intensity of marine heatwaves (MHWs) and blooms of the harmful algal species, Alexandrium pacificum, are increasing in areas where there are natural reefs and commercial farms of the mussel, Perna canaliculus. In this study, we assessed the whole organism, tissue and molecular-level response of juvenile (spat) P. canaliculus exposed to these abiotic and biotic stressors, alone and together.
View Article and Find Full Text PDFEcotoxicol Environ Saf
January 2025
MOE Key Laboratory of Marine Genetics and Breeding, College of Marine Life Sciences (Qingdao 266003), and Key Laboratory of Tropical Aquatic Germplasm of Hainan Province, Sanya Oceanographic Institution (Sanya 572024), Ocean University of China, China. Electronic address:
Heat shock proteins (Hsps) are highly conserved molecular chaperones with essential roles against biotic and abiotic stressors. A large set of co-chaperons comprising J-domain proteins (DnaJs) regulate the ATPase cycle of Hsp70s with Hsp90s, together constituting a dynamic and functionally versatile network for protein folding/unfolding and regulation. Marine bivalves could accumulate and tolerate paralytic shellfish toxins (PSTs), the well-noted neurotoxins generated during harmful algal blooms.
View Article and Find Full Text PDFPediatr Pulmonol
January 2025
Department of Pediatrics & Kawasaki Disease Research Center, University of California San Diego (UCSD) & Rady Children's Hospital, San Diego, California, USA.
Importance: There is growing understanding that Social Determinants of Health (SDH) impact on the outcomes of different pediatric conditions. We aimed to determine whether SDH affect the severity of MIS-C.
Design: Retrospective cohort study, 2021-2023.
Cult Med Psychiatry
December 2024
Department of Political Science, Seattle University, Seattle, USA.
Can the fraught relation between disability and aging ever become untangled? What is the place of the catastrophically disabled in a time when giving voice and being seen are significant lodestars of political activism? And what becomes of the caregivers, who often labor in silence, and who hope to work well enough just to get through another day? This essay draws on the memoirs of Simone de Beauvoir, Annie Ernaux, Amy Bloom, and my own experiences to show the complicated imbrications of age, disability, and caretaking. I attempt to demonstrate through these experiences that age and disability, which appear to be intimately woven together, are oftentimes misleadingly connected. I suggest that an ethic of vulnerability, rather, is a more useful heuristic that avoids collapsing the categories of age and disability together.
View Article and Find Full Text PDFSyst Appl Microbiol
January 2025
Department of Molecular Ecology, Max Planck Institute for Marine Microbiology, Bremen 28359, Germany. Electronic address:
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