AI Article Synopsis

  • The study examines how the duration of sexual abstinence affects sperm quality in both healthy and pathological samples from men undergoing fertility evaluations.
  • Results indicate that longer abstinence generally leads to higher sperm concentration, but can negatively impact sperm motility, particularly in normal and teratozoospermic samples.
  • Recommendations for optimal abstinence duration vary based on specific sperm quality parameters being targeted for improvement.

Article Abstract

Background: The impact of sexual abstinence on sperm quality, particularly in pathological cases, is a subject of debate. We investigated the link between abstinence duration and semen quality in both normal and pathological samples.

Methods: We analyzed semen samples from 4423 men undergoing fertility evaluation, comprising 1256 samples from healthy individuals and 3167 from those with conditions such as oligozoospermia, asthenozoospermia, teratozoospermia, or a combination of these factors, namely oligoasthenoteratozoospermia (OAT). Parameters including sperm concentration, the percentage of progressively motile spermatozoa, total motile sperm count, and the percentage of spermatozoa with normal morphology were assessed at various abstinence durations (each day, 0-2, 3-7, and >7 days).

Results: Extended abstinence correlated with higher sperm concentration overall ( < 0.001), except in oligozoospermia. Longer abstinence reduced progressive motility in normal ( < 0.001) and teratozoospermic samples ( < 0.001). Shorter abstinence was linked to higher morphologically normal sperm in normal samples ( = 0.03), while longer abstinence did so in oligoasthenoteratozoospermic samples ( = 0.013).

Conclusion: The findings suggest that a prolonged abstinence time is linked to higher sperm concentration, while optimal sperm motility is observed after shorter abstinence periods. However, results regarding morphology remain inconclusive. Recommendations on abstinence duration should be tailored based on the specific parameter requiring the most significant improvement.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10890102PMC
http://dx.doi.org/10.3390/life14020188DOI Listing

Publication Analysis

Top Keywords

sperm concentration
12
abstinence
10
normal samples
8
sperm
8
abstinence duration
8
higher sperm
8
longer abstinence
8
shorter abstinence
8
linked higher
8
normal
6

Similar Publications

Aim: To determine the effects of oral antibiotics and anti-inflammatory agents on semen parameters and the sperm DNA fragmentation index (DFI).

Methods: Ninety-eight men with infertility diagnosis were included. The participants submitted two semen samples, before and at least two months after treatment.

View Article and Find Full Text PDF

Di (2-ethylhexyl) phthalate reduces sperm motility by decreasing sperm tail energy supply.

Ecotoxicol Environ Saf

January 2025

Department of Toxicology, School of Public Health; Suzhou Hospital of Anhui Medical University, Hefei 230032, China; Key Laboratory of Environmental Toxicology of Anhui Higher Education Institutes, Hefei 230032, China. Electronic address:

Di (2-ethylhexyl) phthalate (DEHP) is widespread in the environment. It can impair sperm function through damaging the sperm development process. However, few studies have focused on the sperm tail that is directly related to sperm motility.

View Article and Find Full Text PDF

Bisphenol F (BPF) exposure impairs sperm quality and offspring development in male zebrafish.

Toxicol Appl Pharmacol

January 2025

Department of Preventive Medicine, Shantou University Medical College, Shantou 515041, Guangdong, China. Electronic address:

Background: Bisphenol F (BPF), a substitute for bisphenol A (BPA), is widely used in consumer products, increasing the potential for environmental exposure. Our study investigated the reproductive effects of BPF on adult male zebrafish and explored its toxicological mechanisms, as well as its intergenerational effects.

Methods: Adult male zebrafish were exposed to BPF concentrations of 0, 50, 500, 2500, and 5000 nM for 21 days.

View Article and Find Full Text PDF

Hormonal Regulation of Urokinase- and Tissue-Type Plasminogen Activator in Mouse Sertoli Cells.

Mol Reprod Dev

January 2025

Department of Anatomy, Histology, Forensic Medicine and Orthopedic, Section of Histology, Sapienza University of Rome, Rome, Italy.

A role for the plasminogen activator (PA) system has been postulated in mammalian gonads, considering the complex process of morphogenesis these organs undergo during their development. Our results show that mouse Sertoli cells under basal conditions produce both types of PA, tissue-type PA (tPA) and urokinase-type PA (uPA), and hormonal treatments increase the production of both enzymes. The increased enzyme secretion does not correlate with a parallel increase in their mRNAs.

View Article and Find Full Text PDF

Although considered an "eco-friendly" biodegradable plastic, polylactic acid (PLA) microplastic (PLA-MP) poses a growing concern for human health, yet its effects on male reproductive function remain underexplored. This study investigated the reproductive toxicity of PLA in male mice and its potential mechanisms. To this end, our in vivo and in vitro experiments demonstrated that after degradation in the digestive system, a significant number of PLA-MP-derived nanoparticles could penetrate the blood-testis barrier (BTB) and localize within the spermatogenic microenvironment.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!