The aim of this clinical study was to compare the occlusal caries detection (OCD) performance of the intraoral scanners (IOSs) Trios 4 (TIO, 3Shape) and Emerald S (EME, Planmeca) and the Diagnocam (DIA, KaVo) with the established visual (WHO) examination (VIS, reference method). Between 08/2022 and 02/2023, 60 children (mean age 9.6 ± 2.5 years) were examined as part of their regular dental checkups. OCD was performed at the tooth level, separately for primary and permanent unrestored teeth. Furthermore, two thresholds were analyzed: sound versus overall caries (pooled data of enamel and dentin caries, TH1) and pooled data of sound and enamel caries versus dentin caries (TH2). The best agreement with the reference method (reliability) in both dentitions was obtained for DIA (ĸ = 0.829/ĸ = 0.846; primary/permanent teeth), followed by EME (ĸ = 0.827/ĸ = 0.837) and TIO (ĸ = 0.714/ĸ = 0.680). Similar results were shown for the diagnostic quality (sensitivity, specificity and area under the curve of the receiver operating characteristic curve), with higher values for TH1 than for TH2. Both IOSs and the DIA showed worse results than the reference method VIS. Currently, IOS should be used as an additional caries detection tool, especially for visualization, and cannot be recommended as a basic tool for diagnosis or invasive/noninvasive therapy decisions in OCD.
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http://dx.doi.org/10.3390/jcm13040925 | DOI Listing |
J Dent Sci
January 2025
School of Dentistry, College of Oral Medicine, Taipei Medical University, Taipei, Taiwan.
Background/purpose: Salivary microbiome has become a surrogate indicator of oral disease due to its collective reservoirs and convenience in sampling. However, failed clinical trials often lead to wastes of resources, indicating a need for preclinical models. In this pilot study, we aimed to compare the salivary microbiome by metagenomics analysis before and after lysogeny broth culture for prospective translational studies.
View Article and Find Full Text PDFInt J Clin Pediatr Dent
December 2024
Department of Pediatric and Preventive Dentistry, RajaRajeswari Dental College and Hospital, Bengaluru, Karnataka, India.
Background/aim: Early childhood caries (ECC) is a prevalent dental disease, influenced by genetic and environmental factors. Human leukocyte antigens (HLA) have been suggested as a predisposing factor. This study aims to estimate and correlate HLA-DR and HLA-DQ activity in the saliva of caries-active and caries-free children, potentially aiding disease diagnosis and prevention.
View Article and Find Full Text PDFBMC Oral Health
January 2025
Center for Plastic & Reconstructive Surgery, Department of Stomatology, Affiliated People's Hospital, Zhejiang Provincial People's Hospital, Hangzhou Medical College, Hangzhou, Zhejiang, China.
Background: The purpose of this study was to evaluate the validity of near-infrared light reflection for detecting different depths of proximal caries in posterior teeth and to compare it with commonly used clinical oral examinations and bitewing radiography images.
Methods: Twenty-six patients with a total of 516 proximal surfaces were included in this study. The ground truth of the proximal caries was determined through a consensus reached by two experienced dentists after an intraoral examination assisted by bitewing radiographs.
Int J Mol Sci
January 2025
Associate Laboratory i4HB-Institute for Health and Bioeconomy, University Institute of Health Sciences-CESPU, 4585-116 Gandra, Portugal.
Oral candidiasis is one of the most common infections in the immunocompromised. Biofilms of species can make treatments difficult, leading to oral infection recurrence. This research aimed to isolate a with anti- effects from the oral cavity.
View Article and Find Full Text PDFChildren (Basel)
December 2024
Department of Pedodontics, Faculty of Dentistry, Ege University, Izmir 35040, Turkey.
Background/objectives: Vitamin D helps the mineralization of bone, teeth, and other calcified tissues by regulating calcium-phosphate metabolism. The nuclear activation of the vitamin D receptor () gene is essential for the effectiveness of vitamin D. The main objective of this study is to determine the role of vitamin D levels and gene variants in dental caries.
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