Purpose: Unenhanced abdominal CT constitutes the diagnostic standard of care in suspected urolithiasis. Aiming to identify potential for radiation dose reduction in this frequent imaging task, this experimental study compares the effect of spectral shaping and tube voltage modulation on image quality.
Methods: Using a third-generation dual-source CT, eight cadaveric specimens were scanned with varying tube voltage settings with and without tin filter application (Sn 150, Sn 100, 120, 100, and 80 kVp) at three dose levels (3 mGy: standard; 1 mGy: low; 0.5 mGy: ultralow). Image quality was assessed quantitatively by calculation of signal-to-noise ratios (SNR) for various tissues (spleen, kidney, trabecular bone, fat) and subjectively by three independent radiologists based on a seven-point rating scale (7 = excellent; 1 = very poor).
Results: Irrespective of dose level, Sn 100 kVp resulted in the highest SNR of all tube voltage settings. In direct comparison to Sn 150 kVp, superior SNR was ascertained for spleen (p ≤ 0.004) and kidney tissue (p ≤ 0.009). In ultralow-dose scans, subjective image quality of Sn 100 kVp (median score 3; interquartile range 3-3) was higher compared with conventional imaging at 120 kVp (2; 2-2), 100 kVp (1; 1-2), and 80 kVp (1; 1-1) (all p < 0.001). Indicated by an intraclass correlation coefficient of 0.945 (95% confidence interval: 0.927-0.960), interrater reliability was excellent.
Conclusions: In abdominal CT with maximised dose reduction, tin prefiltration at 100 kVp allows for superior image quality over Sn 150 kVp and conventional imaging without spectral shaping.
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http://dx.doi.org/10.1186/s12880-024-01228-1 | DOI Listing |
Eur Radiol Exp
January 2025
Unit of Medical Physics, Pisa University Hospital "Azienda Ospedaliero-Universitaria Pisana", Pisa, Italy.
Background: Photon-counting detector (PCD) technology has the potential to reduce noise in computed tomography (CT). This study aimed to carry out a voxelwise noise characterization for a clinical PCD-CT scanner with a model-based iterative reconstruction algorithm (QIR).
Methods: Forty repeated axial acquisitions (tube voltage 120 kV, tube load 200 mAs, slice thickness 0.
This study aims to explore the feasibility of applying the "Three-Low" technique (low injection rate, low iodine contrast volume, low radiation dose) in coronary CT angiography (CCTA). We prospectively collected data from 90 patients who underwent CCTA at our hospital between 2021 and 2024. The patients were randomly assigned to either the experimental group (n = 45) or the control group (n = 45).
View Article and Find Full Text PDFSci Rep
December 2024
School of Energy Science and Engineering, Central South University, Changsha, 410083, China.
A three-dimensional numerical model of the vacuum sintering furnace was established, combined with the custom program of temperature-voltage feedback regulation. Through simulationand experimental validation, the heating and holding stage as well as the thermal hysteresis phenomenon of the furnace were analyzed, a dimensionless quantity of hysteresis temperature difference was proposed and calculated, the distribution of the electric field and temperature uniformity of the furnace were discussed in detail, while the structural improvement approach was proposed based on simulation. The results show that: during the heating process, the maximum of thermal hysteresis temperature difference between the graphite cylinder and the heating tube is 0.
View Article and Find Full Text PDFRev Sci Instrum
December 2024
2nd Institute of Physics B and JARA-FIT, RWTH Aachen University, 52074 Aachen, Germany.
Low-temperature scanning tunneling spectroscopy is a key method to probe electronic and magnetic properties down to the atomic scale, but suffers from extreme vibrational sensitivity. This makes it challenging to employ closed-cycle cooling with its required pulse-type vibrational excitations, albeit this is mandatory to avoid helium losses for counteracting the continuously raising helium prices. Here, we describe a compact ultra-high vacuum scanning tunneling microscope (STM) system with an integrated primary pulse tube cooler (PTC) for closed-cycle operation.
View Article and Find Full Text PDFTalanta
December 2024
Applied Analytical Chemistry, University of Duisburg-Essen, Universitatsstr. 5, 45141, Essen, Germany; Teaching and Research Center for Separation, University of Duisburg-Essen, Universitatsstr. 5, 45141, Essen, Germany. Electronic address:
The monitoring of phthalate esters (PAEs) is challenging due to background contamination as well as the low selectivity observed when analyzing them by gas chromatography coupled to mass spectrometry (GC-MS) using electron ionization (EI). In this sense, alternative and soft ionization techniques could help to enhance the performance of the analytical determinations of PAEs in food samples. In this work, the use of a novel and soft ionization technique tube plasma ionization (TPI) has been explored to enhance the selectivity and sensitivity in the determination of PAEs in drinking water samples with GC-MS.
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