Dangers and therapeutic difficulties of intracranial hemangioma in infants: A CARE case report.

Eur Ann Otorhinolaryngol Head Neck Dis

Service d'ORL et Chirurgie Cervicofaciale Pédiatrique, Hôpital Necker-Enfants-Malades, Assistance publique-Hôpitaux de Paris, Université Paris Descartes, Paris, France.

Published: August 2024

Introduction: Description of neurological complications induced by intracranial hemangioma in infants and by the initiation of beta-blocker treatment (propranolol).

Observation: A 2-month-old infant was referred for grade 5 non-congenital unilateral peripheral facial palsy. Work-up revealed ipsilateral profound hearing loss and two intracranial hemangiomas: one in the ipsilateral internal auditory canal (IAC), the other in the cerebellum opposite the nodule of vermis. Initial treatment with a beta-blocker (propranolol 1mg/kg/day for 1month, then 3mg/kg/day) resulted in disappearance of symptoms and regression of lesions within 8weeks. At 20months after introduction of maintenance therapy (propranolol 3mg/kg/day), two asthma attacks occurred, leading to initiation of fluticasone and continuation of the beta-blocker. Thirty months after discontinuation of treatment, no further progression was noted.

Discussion: Unilateral facial palsy in an infant suggests a number of diagnoses. MRI revealed IAC hemangioma. The choice of dosage and duration of treatment was based on a review of the literature and a strategy defined in multidisciplinary consultation.

Download full-text PDF

Source
http://dx.doi.org/10.1016/j.anorl.2024.02.001DOI Listing

Publication Analysis

Top Keywords

intracranial hemangioma
8
hemangioma infants
8
facial palsy
8
dangers therapeutic
4
therapeutic difficulties
4
difficulties intracranial
4
infants care
4
care case
4
case report
4
report introduction
4

Similar Publications

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!