Cannabis vaporization is useful for individuals requiring fast-acting method of cannabis administration and for individuals using smoked cannabis as a harm reduction tool. There is a need for guidance on how to assess if a patient is a vaporization candidate and how to safely initiate and monitor cannabis vaporization. An overview of safe cannabis vaporization, including practical guidance and tactics to promote the lowest-risk use, is provided. This review was developed through a combination of expert clinical opinion and reviewing the available literature. Dried cannabis vaporizers and metered-dose inhalers are recommended to be used over other vaporization devices. Assessing the benefit versus risks of vaporized cannabis and providing guidance for choosing a vaporization device, choosing a cannabis chemovar, and employing a mindful vaping technique are important steps in the safe utilization of vaporized cannabis. Dosing optimization and monitoring to limit adverse events and improve symptom control are essential. The utilization of cannabis vaporization presents an important opportunity for clinicians and other health professionals to help facilitate safer cannabis administration and reduce the prevalence of smoked cannabis.
Center for Tobacco Control Research and Education, University of California, San Francisco, San Francisco, CA, USA; Division of General Internal Medicine, Department of Medicine, University of California, San Francisco, San Francisco, CA, USA.
Significance: Vaping both nicotine and cannabis in the past 30 days (co-vaping) is common among young adults. It is unclear which co-vaping patterns may increase substance use and dependence. We examined day-level associations between vaping patterns with vaping quantity.
The study investigates the immediate cardiovascular effects of different cannabis inhalation methods and cannabinoid profiles, focusing on THC and CBD.
Researchers assessed arterial stiffness, endothelial function, and cardiac performance in 22 healthy cannabis users before and after using THC-dominant and CBD-dominant strains.
Results show that THC use significantly increases heart rate and blood pressure, while CBD does not affect these cardiovascular markers, indicating potential risks associated with THC consumption.
Background: Use of cannabis and nicotine is at record levels among young adults, and health consequences vary by route of administration. However, there is a paucity of research characterizing use of both substances, especially among individuals of racial/ethnic minoritized identities.
Method: Participants (N = 1,032; age 18-25 years) completed a cross-sectional survey administered through an online panel in 2021 in eight U.
The prevalence of electronically vaporized cannabidiol (CBD) use is rising in many countries. However, few regulatory frameworks exist for inhaled CBD, and this lack of oversight may not protect consumers from adverse consequences. We generated a representative map of several global consumer vaporized CBD markets by collating data concerning cannabinoid levels, including CBD and Δ-tetrahydrocannabinol, from the scientific literature.
The study investigates the impact of chronic exposure to cannabis high in Δ-THC on the effectiveness of Adderall, a common prescription psychostimulant, in male and female mice.
Mice exposed to vaporized cannabis showed decreased brain activation in response to Adderall, indicating a potential reduction in sensitivity to the drug, particularly in areas associated with dopamine signaling.
After a two-week period without cannabis, the mice exhibited no significant differences in Adderall response, suggesting that the effects of cannabis exposure might be reversible.
