Antibiotic Prescribing in Dental Medicine-Best Practices for Successful Implementation.

Trop Med Infect Dis

Department of Implant-Prosthetic Therapy, Faculty of Dentistry, Carol Davila University of Medicine and Pharmacy, 17-23 Calea Plevnei, 010221 Bucharest, Romania.

Published: January 2024

With rising rates of antimicrobial resistance throughout the world, it is time to revisit antibiotic prescribing policies and practices, and dentistry is an important area for focused intervention, as it accounts for up to 15% of all antimicrobial prescriptions. In this narrative review, we have analyzed the current state of the knowledge, attitudes, and practice regarding antimicrobial use among dental professionals, and we have identified a set of seven recurring themes that drive inappropriate antibiotic prescribing in dental medicine. These include: 1. Prescribing antibiotics to delay or avoid dental treatment. 2. Overlooking the 5Ds-dental treatment (source control), dental condition (indication), drug (antibiotic choice), dose, and duration. 3. Relying on education from the distant past and on previous experience. 4. The heterogeneity of (too many) guideline recommendations leads to confusion and over-prescribing. 5. Decreased access to guideline information in private practice. 6. Psychological factors such as pressure to prescribe, comfort prescribing and the weekend effect, and 7. Feeling removed from antimicrobial resistance and externalizing responsibility. Based on the existing knowledge, we propose a framework based on four key pillars for focused intervention: 1. Education. 2. Internalizing responsibility. 3. Recognizing recurring counter-productive practices, and 4. Addressing recurring counter-productive practices. This framework can be applied in different dental settings to ensure best practices for the successful implementation of rational antimicrobial prescribing.

Download full-text PDF

Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10892960PMC
http://dx.doi.org/10.3390/tropicalmed9020031DOI Listing

Publication Analysis

Top Keywords

antibiotic prescribing
12
prescribing dental
8
practices successful
8
successful implementation
8
antimicrobial resistance
8
focused intervention
8
recurring counter-productive
8
counter-productive practices
8
dental
6
practices
5

Similar Publications

Long-term forecast for antibacterial drug consumption in Germany using ARIMA models.

Naunyn Schmiedebergs Arch Pharmacol

January 2025

Hannover Medical School, Institute of Pharmacology, D-30625, Hannover, Germany.

The increasing supply shortages of antibacterial drugs presents significant challenges to public health in Germany. This study aims to predict the future consumption of the ten most prescribed antibacterial drugs in Germany up to 2040 using ARIMA (Auto Regressive Integrated Moving Average) models, based on historical prescription data. This analysis also evaluates the plausibility of the forecasts.

View Article and Find Full Text PDF

Re-evaluating Presumptive Treatment with Doxycycline/ Azithromycin in Children With Acute Febrile Illness in a Scrub Typhus Endemic Region: A Cross-Sectional Study.

Indian Pediatr

January 2025

ICMR Regional Medical Research Centre, Gorakhpur, Uttar Pradesh, India. Correspondence to: Dr Manoj Murhekar, Director-in-Charge, ICMR-Regional Medical Research Centre, Gorakhpur, Uttar Pradesh, India 273013.

Objective: To estimate the proportion of children with acute febrile illness (AFI) attending the peripheral health facilities in Gorakhpur, Uttar Pradesh, India, due to Orientia tsutsugamushi (Ots) and re-evaluate the strategy of presumptive administration of doxycycline/azithromycin (PDA) to patients with AFI.

Methods: Children aged 2-18 years with AFI attending 16 peripheral health facilities in Gorakhpur, Uttar Pradesh, were enrolled in September 2023. Blood samples were tested for O.

View Article and Find Full Text PDF
Article Synopsis
  • Addressing the increasing concern of antimicrobial resistance (AMR) requires better management of antibiotic prescriptions, and monitoring practices in hospitals can help optimize their use, especially in smaller facilities with limited resources.
  • This study performed point prevalence surveys (PPSs) in two hospitals in Mexico to assess antibiotic prescribing patterns and collected data from 127 patients across various ward types.
  • Results showed high rates of antibiotic use (60.4% and 70.5% at hospitals H1 and H2, respectively), with common indications being medical and preoperative prophylaxis, primarily based on empirical prescribing without sufficient post-prescription reviews.
View Article and Find Full Text PDF

Antibiotic prescribing patterns at outpatient clinics in Western and Coastal Kenya.

PLOS Glob Public Health

January 2025

Department of Pediatrics, Division of Pediatric Infectious Diseases, Stanford University School of Medicine, Stanford, California, United States of America.

Antimicrobial resistant pathogens are a leading cause of morbidity and mortality worldwide, with overuse and misuse of antimicrobials being key contributors. We aimed to identify factors associated with antibiotic prescriptions among patients presenting to clinics in Kenya. We performed a retrospective, descriptive cohort study of persons presenting to outpatient clinics in Western and Coastal Kenya, including symptoms, physical exams, clinician assessments, laboratory results and prescriptions.

View Article and Find Full Text PDF

Nirmatrelvir/ritonavir is a novel drug combination authorized by the US Food and Drug Administration for the treatment of coronavirus disease 2019 (COVID-19). This report describes the case of a patient with a prior history of kidney transplantation who received nirmatrelvir/ritonavir. In this case, sirolimus use was successfully stopped before nirmatrelvir/ritonavir treatment, and the nirmatrelvir/ritonavir trough concentration was determined.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!