The interior problem, a persistent ill-posed challenge in CT imaging, gives rise to truncation artifacts capable of distorting CT values, thereby significantly impacting clinical diagnoses. Traditional methods have long struggled to effectively solve this issue until the advent of supervised models built on deep neural networks. However, supervised models are constrained by the need for paired data, limiting their practical application. Therefore, we propose a simple and efficient unsupervised method based on the Cycle-GAN framework. Introducing an implicit disentanglement strategy, we aim to separate truncation artifacts from content information. The separated artifact features serve as complementary constraints and the source of generating simulated paired data to enhance the training of the sub-network dedicated to removing truncation artifacts. Additionally, we incorporate polar transformation and an innovative constraint tailored specifically for truncation artifact features, further contributing to the effectiveness of our approach. Experiments conducted on multiple datasets demonstrate that our unsupervised network outperforms the traditional Cycle-GAN model significantly. When compared to state-of-the-art supervised models trained on paired datasets, our model achieves comparable visual results and closely aligns with quantitative evaluation metrics.
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http://dx.doi.org/10.3390/e26020101 | DOI Listing |
Sensors (Basel)
December 2024
School of Biomedical Engineering, Southern Medical University, Guangzhou 510515, China.
Megavoltage computed tomography (MVCT) plays a crucial role in patient positioning and dose reconstruction during tomotherapy. However, due to the limited scan field of view (sFOV), the entire cross-section of certain patients may not be fully covered, resulting in projection data truncation. Truncation artifacts in MVCT can compromise registration accuracy with the planned kilovoltage computed tomography (KVCT) and hinder subsequent MVCT-based adaptive planning.
View Article and Find Full Text PDFPhys Med Biol
January 2025
Department of Radiology, University of Chicago, 5841 South Maryland Avenue, Chicago, IL 60637, USA, Chicago, 60637, UNITED STATES.
Objective: Accurate image reconstruction from data with truncation in X-ray computed tomography (CT) remains a topic of research interest; and the works reported previously in the literature focus largely on reconstructing an image only within the scanning field-of-view (FOV). We develop algorithms to invert the data model with truncation for accurate image reconstruction within the entire subject support or a region slightly smaller than the subject support.
Methods: We formulate image reconstruction from data with truncation as an optimization program, which includes hybrid constraints on image total variation (TV) and image L1-norm for effectively suppressing truncation artifacts.
bioRxiv
December 2024
Department of Ecology and Evolution, University of Chicago, Chicago, IL, USA.
We recently reanalyzed 20 combinatorial mutagenesis datasets using a novel reference-free analysis (RFA) method and showed that high-order epistasis contributes negligibly to protein sequence-function relationships in every case. Dupic, Phillips, and Desai (DPD) commented on a preprint of our work. In our published paper, we addressed all the major issues they raised, but we respond directly to them here.
View Article and Find Full Text PDFRadiat Prot Dosimetry
December 2024
Department of Oral and Maxillofacial Radiology, School of Dentistry, Yasuj University of Medical Sciences, Dr. Shahid Jalil St., Yasuj, Kohgiluyeh and Boyer-Ahmad Province, Iran.
Radiation protection in dental radiography can be achieved by adjusting the image field size, exposure, and filtration parameters, and using protective lead shields. The aim of this study is to assess the radiation dose delivered to the thyroid in a phantom irradiated by an orthopantomogram (OPG) system using Geant4 simulation toolkit. Recently, researchers have been trying to find an alternative material to the lead thyroid shield so that the OPG image has minimal metal artifacts.
View Article and Find Full Text PDFJ Med Imaging Radiat Oncol
November 2024
Department of Radiology, Johns Hopkins University, Baltimore, Maryland, USA.
Visual perceptual artefacts are distortions or illusions in medical image interpretation arising from the human visual system rather than hardware or imaging acquisition processes. These artefacts, emerging at various visual processing stages, such as the retina, visual pathways, visual cortex, and cognitive interpretation stages, impact the interpretation of cardiothoracic images. This review discusses artefacts including Mach bands, Dark Rim, Background Effects, Ambiguous Figures, Subjective Contours, and the Parallax Effect.
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