A non-peptide-based fluorescent probe capable of sensitively visualizing asparagine endopeptidase.

Chem Commun (Camb)

State Key Laboratory of Fine Chemicals, Frontiers Science Centre for Smart Materials Oriented Chemical Engineering, Dalian University of Technology, Dalian 116024, China.

Published: March 2024

The non-peptide-based fluorescent probe QMC11 is capable of specifically targeting asparagine endopeptidase (AEP) and imaging cellular endogenous AEP. The motion of the probe can be restricted by AEP to activate fluorescence while keeping a low background signal.

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Source
http://dx.doi.org/10.1039/d3cc05419eDOI Listing

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