AI Article Synopsis
- The study analyzes glycemic control and anthropometric data in children with type 1 diabetes using the MiniMed 780G Advanced Hybrid Closed Loop system for two years.
- The research involved 50 children, comparing their glucose levels and growth metrics over time, with no significant changes in their time in the target glucose range or BMI z-scores during the observation period.
- The findings indicate that glycemic control remained stable over two years, likely aided by an increase in insulin autocorrection, which helped maintain weight and metabolic health in these children.
Article Abstract
Background And Aims: MiniMed 780G is the first Advanced Hybrid Closed Loop (AHCL) system in Poland, approved in the EU in 2020. To date, observations of glycemic control up to 12 months have been published. This study aimed to analyze glycemic control and anthropometric parameters in children and adolescents with type 1 diabetes (T1D) after two years of using the AHCL system.
Materials And Methods: We prospectively collected anthropometric data, pump, and continuous glucose records of fifty T1D children (9.9 ± 2.4 years, 24 (48%) boys, T1D for 3.9 ± 2.56 years) using an AHCL system. We compared the two-week AHCL records obtained after AHCL enrollment with data 6, 12, and 24 months after starting AHCL.
Results: Time in range (70-180 mg/dl) and BMI z-score did not change during the 2 years of observation (p>0.05). The percentage of autocorrection in total daily insulin increased significantly (p<0.005).
Conclusion: Glycemic control in the investigated group of children with T1D treated with the AHCL system for 2 years remained stable. Children in this group maintained weight and optimal metabolic control, most likely due to autocorrection boluses.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10882083 | PMC |
| http://dx.doi.org/10.3389/fendo.2024.1332418 | DOI Listing |
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