Ie Jue is one of the geothermal manifestation of hot water and fumaroles in the northern zone of Mount Seulawah Agam. Because hot water in the Ie Jue manifestation is derived from meteoric water, the presence of Ie Jue hot springs is determined by rain intensity and surface infiltration rates in the vicinity of the manifestation. The purpose of this research is to determine the rate of precipitation infiltration and its link to the type of flora that grows around the manifestation. Ie Jue. The 100 m line transect approach was used to determine sampling locations. Transects were placed in stratified sampling based on the four cardinal directions from the manifestation's center, namely east, south, west, and north. In each transect, three sampling stations were placed at intervals of 0 m, 50 m, and 100 m from the manifestation's midpoint. In each transect, three sampling stations were placed at intervals of 0 m, 50 m, and 100 m from the manifestation's midpoint. At each sampling point, the vegetation type was identified, and soil temperature, moisture, pH, texture, density and organic C were measured. A single ring infiltrometer was used to quantify infiltration rate at each sampling location, and the Horton equation was used to compute infiltration capacity. The results showed that the type of tree vegetation found in the south had the maximum infiltration rate of 54 cm/h - 28.8 cm/h with a constant interval of 40 min, followed by an infiltration rate of 44.4 cm/h - 8.4 cm/h for 45 min in the north with pole vegetation type. In comparison to other regions, the south and north have exceptionally quick infiltration criteria (36.87 cm/h and 29.88 cm/h, respectively). When compared to poles, shrubs, and herbs, tree-type vegetation had the highest infiltration rate. The results showed that vegetation type, soil moisture, bulk density, and soil organic C are the most important elements influencing infiltration in the Ie jue hot spring area.
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http://dx.doi.org/10.1016/j.heliyon.2024.e25783 | DOI Listing |
JAMA Cardiol
January 2025
National Amyloidosis Centre, Division of Medicine, University College London, Royal Free Hospital, London, United Kingdom.
Importance: Patients with transthyretin (ATTR) cardiac amyloid infiltration are increasingly diagnosed at earlier disease stages with no heart failure (HF) symptoms and a wide range of cardiac amyloid infiltration.
Objective: To characterize the clinical phenotype and natural history of asymptomatic patients with ATTR cardiac amyloid infiltration.
Design, Setting, And Participants: This cohort study analyzed data of all patients at 12 international centers for amyloidosis from January 1, 2008, through December 31, 2023.
mSystems
January 2025
Key Laboratory of Microbiology and Parasitology of Education Department of Guizhou, Guizhou Medical University, Guiyang, China.
Unlabelled: The gut microbiota is closely associated with inflammatory bowel disease (IBD) and colorectal cancer (CRC). Probiotics such as (CB) or (AKK) have the potential to treat inflammatory bowel disease (IBD) or colorectal cancer (CRC). However, research on the combined therapeutic effects and immunomodulatory mechanisms of CB and AKK in treating IBD or CRC has never been studied.
View Article and Find Full Text PDFPathol Oncol Res
January 2025
Department of Nuclear Medicine, Prof. Dr. Cemil Taşcıoğlu City Hospital, University of Health Sciences, Istanbul, Türkiye.
Background And Objectives: This study aims to evaluate the correlation between Tumor-Infiltrating Lymphocyte (TIL) levels and Fluorine-18 fluorodeoxyglucose (F-FDG) metabolic parameters, including spleen and bone marrow FDG uptake and tumor heterogeneity in non-luminal breast cancers (NLBC), and to elucidate their association with survival outcomes.
Methods: We retrospectively analyzed data from 100 females with stage 2-4 NLBC who underwent pretreatment F-FDG Positron emission tomography-computed tomography (PET/CT). TIL was scored based on Hematoxylin-Eosin-stained specimens and F-FDG PET metabolic parameters, including maximum standardized uptake value (SUVmax), mean standardized uptake value (SUVmean), metabolic tumor volume (MTV), total lesion glycolysis (TLG), liver, spleen, and bone marrow FDG uptake were calculated.
Front Oncol
January 2025
Department of Pediatrics, Children's Healthcare of Atlanta, Atlanta, GA, United States.
Background: Pediatric low-grade gliomas (pLGGs) have an overall survival of over 90%; however, patients harboring a BRAF alteration may have worse outcomes, particularly when treated with classic chemotherapy. Combined BRAF/MEK inhibition following incomplete resection demonstrated improved outcome in BRAF altered pLGG compared to combined carboplatin/vincristine chemotherapy and is now considered the standard FDA-approved treatment for this group of tumors. The aim herein was to investigate the efficacy and tolerability of single agent BRAF inhibitor treatment in BRAF altered pLGG.
View Article and Find Full Text PDFMater Today Bio
February 2025
Stomatology Department, The Fifth Affiliated Hospital, Sun Yat-sen University, Zhuhai, Guangdong, China.
Oral squamous cell carcinoma (OSCC) remains a formidable challenge due to high recurrence rates and limited efficacy of conventional treatments. Immunotherapy holds potential, but its effectiveness is often restricted by low patient responsiveness. This study presents a novel therapeutic strategy using GSH/pH-responsive copper-based cascade nanocomplexes to induce immunogenic cell death (ICD) in OSCC.
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