Digital PET/CT systems with a long axial field of view have become available and are emerging as the current state of the art. These new camera systems provide wider anatomic coverage, leading to major increases in system sensitivity. Preliminary results have demonstrated improvements in image quality and quantification, as well as substantial advantages in tracer kinetic modeling from dynamic imaging. These systems also potentially allow for low-dose examinations and major reductions in acquisition time. Thereby, they hold great promise to improve PET-based interrogation of cardiac physiology and biology. Additionally, the whole-body coverage enables simultaneous assessment of multiple organs and the large vascular structures of the body, opening new opportunities for imaging systemic mechanisms, disorders, or treatments and their interactions with the cardiovascular system as a whole. The aim of this perspective document is to debate the potential applications, challenges, opportunities, and remaining challenges of applying PET/CT with a long axial field of view to the field of cardiovascular disease.
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http://dx.doi.org/10.2967/jnumed.123.266858 | DOI Listing |
Int J Lang Commun Disord
January 2025
Division of Communication Sciences and Disorders, University of Cape Town, Rondebosch, South Africa.
Background: There is a global need for synthetic speech development in multiple languages and dialects, as many children who cannot communicate using their natural voice struggle to find synthetic voices on high-technology devices that match their age, social and linguistic background.
Aims: To document multiple stakeholders' perspectives surrounding the quality, acceptability and utility of newly created synthetic speech in three under-resourced South African languages, namely South African English, Afrikaans and isiXhosa.
Methods & Procedures: A mixed methods research design was selected.
Int J Equity Health
January 2025
Department of Health Management, School of Health Management, Southern Medical University, Guangzhou, 510515, China.
Objective: Perfect policy system support is the key to effective work, and policy evaluation can provide theoretical basis for policy revision. This study aims to quantitatively evaluate the two-way referral policy in China and thus improve the policy system of two-way referral.
Methods: This research focuses on 14 two-way referral policies published from 2007 to 2021.
BMJ Support Palliat Care
January 2025
Department of Oncology, County Hospital Ryhov, Jönköping, Jonkoping County, Sweden
Neutropenia is a common chemotherapy-induced symptom that can lead to febrile neutropenia (FN) and infection. The aim of this study was to assess the incidence of neutropenia, FN, documented infection with neutropenia and fever associated with early-stage breast cancer (BC) in a real-life setting. This retrospective study includes 88 women with early-stage BC who received a first dose of epirubicin plus cyclophosphamide with or without 5-fluorouracil.
View Article and Find Full Text PDFBehav Anal Pract
December 2024
Center for Autism and Related Disorders, Inc, Woodland Hills, Los Angeles, CA USA.
Perspective taking is a critical repertoire for navigating social relationships and consists of a variety of complex verbal skills, including socially adaptive forms of deception. Detecting and being able to use socially adaptive deception likely has many practical uses, including defending oneself against bullying, telling white lies to avoid hurting others' feelings, keeping secrets and bluffing during games, and playing friendly tricks on others. Previous research has documented that some Autistic children have challenges identifying deception and playfully deceiving others (Reinecke et al.
View Article and Find Full Text PDFJ Family Med Prim Care
December 2024
Department of Pharmacology, Soban Singh Jeena Government Institute of Medical Sciences and Research, Almora, Uttarakhand, India.
Background: The Family Adoption Programme (FAP) aims to provide a learning opportunity to Indian medical graduates towards community-based health care. This study describes the perspective of medical undergraduate students towards the FAP implementation at the government medical college in Almora.
Methods: An observational study was conducted on the students of phases I and II in the government medical college, Almora, on the hurdles and facilitators of FAP via Google Form.
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