AI Article Synopsis
- - A 30-year-old man with relapsing-remitting multiple sclerosis experienced psoriasiform dermatitis after his second ocrelizumab treatment, which resolved with topical treatments and stopping the medication.
- - There is a rising number of reports linking psoriasiform rashes to ocrelizumab use, potentially caused by B-cell depletion and T-cell overregulation.
- - Currently, skin-related side effects are not addressed in the risk management plans for anti-CD20 therapies like ocrelizumab in multiple sclerosis patients.
Article Abstract
We present a case of a 30-year-old man with relapsing-remitting multiple sclerosis who developed psoriasiform dermatitis following his second course of ocrelizumab. This resolved with topical therapies and discontinuation of treatment. Cases of psoriasiform rashes have been increasingly reported in the use of ocrelizumab and are possibly due to B-cell (CD20) depletion and T-cell overregulation. Nevertheless, skin-related adverse reactions are not yet considered in the risk management plans of anti-CD20 treatments in multiple sclerosis.
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| http://dx.doi.org/10.1177/13524585241232277 | DOI Listing |
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