A Case of Squamoid Eccrine Ductal Carcinoma of the Auricle Mimicking Perichondritis.

Ear Nose Throat J

Department of Otorhinolaryngology-Head and Neck Surgery, College of Medicine, Jeonbuk National University School of Medicine, Jeonju, Korea.

Published: February 2024

AI Article Synopsis

  • Squamoid eccrine ductal carcinoma (SEDC) is a rare form of eccrine carcinoma, with only 38 documented cases, of which only 6 are located in the ear.
  • This text highlights a unique case of SEDC that is found in the dermal and subcutaneous layers without affecting the epidermis, which is unusual.
  • The histopathological characteristics of SEDC can lead to confusion with acute perichondritis, making accurate diagnosis challenging for clinicians.

Article Abstract

The subtype of eccrine carcinoma known as squamoid eccrine ductal carcinoma (SEDC) is rare; only 38 cases, including only 6 cases in the ear, have been documented in the literature. This may be the first case to focus on the fact that SEDC, located within the dermal and subcutaneous layers, spares the epidermis histopathologically, which can cause clinicians to confuse SEDC with acute perichondritis.

Download full-text PDF

Source
http://dx.doi.org/10.1177/01455613241234235DOI Listing

Publication Analysis

Top Keywords

squamoid eccrine
8
eccrine ductal
8
ductal carcinoma
8
case squamoid
4
carcinoma auricle
4
auricle mimicking
4
mimicking perichondritis
4
perichondritis subtype
4
subtype eccrine
4
eccrine carcinoma
4

Similar Publications

Squamoid eccrine ductal carcinoma (SEDC) is an unusually rare neoplasm of the skin with a relatively high risk for local recurrence and a potential for metastasis. While typical presentations occur in older, male patients, this case report describes the diagnosis made in a pregnant patient in her third trimester. The clinical presentation, pathology, and treatment course of SEDC are outlined in this article.

View Article and Find Full Text PDF
Article Synopsis
  • Squamoid eccrine ductal carcinoma is a rare tumor with characteristics that fall between squamous cell carcinoma (SCC) and certain sweat gland carcinomas, leading to debates on its classification.
  • The study examined 15 cases of this carcinoma, revealing that most cases had UV signature mutations and TP53 mutations as the most common genetic alterations.
  • Transcriptome analysis indicated that this carcinoma expresses 364 genes more and 525 genes less compared to SCC and sweat gland tumors, reinforcing the idea that it has an intermediate phenotype between these cancer types.
View Article and Find Full Text PDF

Squamoid eccrine ductal carcinoma (SEDC) is a cutaneous adnexal malignancy that is histologically challenging to distinguish from squamous cell carcinoma. We report three cases of this rare entity and review the present literature regarding clinical, histological, and immunohistochemical features. Patients presented with a single nodule or plaque lesion on their back and temple.

View Article and Find Full Text PDF

Mohs surgery for squamoid eccrine ductal carcinoma.

J Cutan Aesthet Surg

January 2024

Central Clinical School, University of Sydney, The Skin Hospital, Darlinghurst, New South Wales, Australia.

Squamous eccrine ductal carcinoma is a rare cutaneous malignancy. It has the potential to locally recur and may occasionally metastasize. It presents a diagnostic challenge given its rare nature and overlapping histopathological features with other cutaneous carcinomas.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!