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DOACs: A perfect fit for patients with bariatric surgery?
Thromb Res
March 2024
Arnold & Marie Schwartz College of Pharmacy and Health Sciences, Department of Pharmacy Practice, Long Island University, New York, NY, USA; Department of Pharmacy, New York-Presbyterian Hospital/Columbia University Irving Medical Center, New York, NY, USA; Department of Pharmacotherapy and Outcome Sciences, Virginia Commonwealth University, Richmond, VA, USA.
DOACs in the Anticoagulation of Mechanical Valves: A Systematic Review and Future Perspectives.
J Clin Med
July 2023
Department of Cardiac Surgery, University Hospitals Leuven, Herestraat 49, 3000 Leuven, Belgium.
Unlabelled: Valvular heart disease is a common disease often necessitating valve replacement. Mechanical heart valves (MHVs) are often used in younger patients because of their longer durability. Their main disadvantage is the need for lifelong anticoagulation.
View Article and Find Full Text PDFDirect oral anticoagulants (DOACs) are replacing warfarin and other vitamin K antagonists for a wide range of indications. Advantages of DOAC therapy are fewer food and drug interactions and fixed dosing without routine laboratory monitoring, making DOACs the perfect choice especially for younger patients, in whom the main indication for anticoagulation is prevention and treatment of venous thromboembolism (VTE). Although DOACs are safer and much more convenient than other anticoagulant alternatives, their profile may have drawbacks, especially for younger female patients in whom reproductive issues need special considerations.
View Article and Find Full Text PDFQuality of life in patients with nonvalvular atrial fibrillation treated with oral anticoagulants.
Hematology
December 2021
Research Unit, Basque Health Service (Osakidetza), Debagoiena Integrated Healthcare Organisation, Arrasate-Mondragón, Spain.
Objectives: Health-related quality of life (HRQL) is a key factor in making anticoagulant treatment decisions. The objective of this study was to assess the HRQL of patients with nonvalvular atrial fibrillation by treatment type: direct oral anticoagulants (DOACs) or vitamin K antagonists (VKAs).
Methods: We carried out a cross-sectional observational study with clinical practice data, gathering demographic and clinical variables.
[Whether or not to use thromboprophylaxis in patients treated with chemotherapy for malignant disease].
Ned Tijdschr Geneeskd
November 2019
Meander Medisch Centrum, afd. Interne Geneeskunde, Amersfoort.
Case Description: A 55-year-old patient with locally advanced pancreatic carcinoma will start Folfirinox. Should he get thromboprophylaxis?
Consideration: Patients with malignant disease have increased risk of venous thromboembolism (VTE). Several types of malignancy, surgery, chemotherapy and metastasis lead to increased risk.
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