Ungewöhnliche klinische Fälle wecken bei praktizierenden Ärzten immer wieder Interesse und ermöglichen es ihnen, ihre Wissensbasis zu erweitern und ihre Fähigkeiten zum klinischen Denken zu verbessern. Der Zweck dieser Studie besteht darin, einen klinischen Fall von Stimmresonanz beim Singen bei einem schwindsüchtigen Teenager aus dem Roman "Der Landarzt" von Honoré de Balzac unter Verwendung induktiver und deduktiver Methoden des klinischen Denkens zu analysieren. Stimmresonanzen beim Singen in Schwindsucht können als pathognomonisches Zeichen für eine kavernöse Tuberkulose gewertet werden, da nur mit dem Bronchus verbundene Hohlräume als Helmholtz-Resonator wirken. Trotz der Einzigartigkeit ist das Gehäuse durchaus realistisch, da es nicht im Widerspruch zu den Gesetzen der Akustik steht. Praktizierende Ärzte verfügen über die Kenntnisse der medizinischen Physik, Morphologie und Physiologie, die zum Verständnis der Pathogenese der klinischen Manifestation einer Lungenhöhle erforderlich sind. Dieser Fall zeigt deutlich die Vor- und Nachteile klinischer Denkmethoden, die in der Praxis eingesetzt werden. Dank der Kombination aus Originalität und Realismus kann der Fall von Stimmresonanz aus Balzacs Roman "Der Landarzt" seinen rechtmäßigen Platz in der persönlichen Sammlung klinischer Fälle eines jeden Lungenarztes einnehmen.
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http://dx.doi.org/10.1055/a-2248-9672 | DOI Listing |
Orthop J Sports Med
January 2025
Balgrist University Hospital, Orthopaedic Department, University of Zurich, Zurich, Switzerland.
Background: Identifying hip instability in symptomatic patients with borderline dysplasia of the hip (BDH) is of paramount importance, as it can influence both surgical decision-making and surgical outcomes. The femoroepiphyseal acetabular roof (FEAR) index is strongly affected by the hip adduction/abduction angle during the pelvic radiograph, which has not yet been considered in the recommended threshold values.
Purpose: To compare the corrected FEAR index in symptomatic patients with BDH treated with pelvic periacetabular osteotomy (PAO) or hip arthroscopy.
Clin Transl Radiat Oncol
November 2024
Department of Medical Oncology, Imaging & Oncology, University Medical Center Utrecht, Utrecht University, Utrecht, the Netherlands.
Colorectal cancer patients with ≤10 unresectable metastases were treated with single-fraction sub-ablative radiotherapy in addition to standard of care systemic therapy in a single-arm, open-label, multicenter, pilot study (SIRIUS) to assess feasibility and safety. Results indicate that radiotherapy combined with systemic therapy is feasible and safe in this population.
View Article and Find Full Text PDFJ Phys Chem A
January 2025
Madrid Institute for Advanced Studies, IMDEA Nanoscience, C/Faraday 9, Ciudad Universitaria de Cantoblanco, Madrid 28049, Spain.
The quest for color-pure emitters for multicolor bioimaging as well as for ultrahigh definition organic light-emitting diodes demands facile design concepts to avoid tedious synthetic or computational trial-and-error procedures. We have recently presented a simple recipe to construct color-pure blue emitters, which combines basic resonance structure and frontier molecular orbital treatments; this recipe applies to multiresonant type emitters and allows to enlarge the chemical space toward novel structural motifs. In the current work, we show that such fundamental considerations further apply to the structurally entirely different family of xanthene dyes.
View Article and Find Full Text PDFACS Nano
January 2025
Max Planck Institute of Microstructure Physics, Weinberg 2, Halle (Saale) 06120, Germany.
Spintronic devices based on the electrical manipulation of magnetic chiral domain walls (DWs) within magnetic nanowires promise advanced memory and logic with high speed and density. However, error-free positioning of the DWs along the magnetic nanowires is challenging. Here, we demonstrate reconfigurable domain wall logic and neuronal devices based on the interaction between the DWs and local magnetic inhibitors that are placed in the proximity of the magnetic nanowire.
View Article and Find Full Text PDFACS Appl Mater Interfaces
January 2025
Henan Key Laboratory of Infrared Materials & Spectrum Measures and Applications, School of Physics, Henan Normal University, Xinxiang 453007, China.
Floating-gate transistors (FGTs), considered the most promising structure among three-terminal van der Waals (vdW) synaptic transistors, possess superiorities in improved data retention, excellent endurance properties, and multibit storage capacity, thereby overcoming the von Neumann bottleneck in conventional computing architectures. However, the dielectric layer in FGT devices typically depends on atomic layer deposition or mechanically transferred insulators, posing several challenges in terms of device compatibility, manufacturing complexity, and performance degradation. Therefore, it is crucial to discover dielectrics compatible with two-dimensional (2D) materials for further simplifying FGT structures and achieving optimal performance.
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