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Non-antibiotic pharmaceuticals are toxic against Escherichia coli with no evolution of cross-resistance to antibiotics.
NPJ Antimicrob Resist
April 2024
Institute of Microbiology and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham, B15 2TT, UK.
Antimicrobial resistance can arise in the natural environment via prolonged exposure to the effluent released by manufacturing facilities. In addition to antibiotics, pharmaceutical plants also produce non-antibiotic pharmaceuticals, both the active ingredients and other components of the formulations. The effect of these on the surrounding microbial communities is less clear.
View Article and Find Full Text PDFCharacterization of Clinicopathological Features and Autoantibody Profiles in Patients with Cutaneous Lupus Erythematous: A Single-Center Retrospective Study.
Am J Clin Dermatol
January 2025
Department of Dermatology, University of Michigan, Ann Arbor, MI, USA.
Background: Cutaneous lupus erythematosus (CLE) is an autoimmune condition characterized by a wide range of clinical manifestations and limited treatment options. There is little research on the impact of commonly used diagnostic tests including antinuclear antibodies (ANA) and extractable nuclear antigens (ENA) on disease course or responsiveness to treatment.
Objective: This single-center retrospective cohort study aims to address this gap by characterizing clinicopathological characteristics, patient demographics, and treatment response among patients with CLE.
Hospital Boarding Creates Critical Shortcomings in Disaster Preparedness.
Health Secur
January 2025
Michael Redlener, MD, FAEMS, is Medical Director, Mount Sinai West Department of Emergency Medicine; Co-Director, Center for Healthcare Readiness; and an Associate Professor, Department of Emergency Medicine; all at Icahn School of Medicine at Mount Sinai, New York City, NY.
Hospital patient boarding in emergency departments has reached unprecedented crisis levels over the past 4 years. Boarding and crowding has been demonstrated by prior literature to have adverse effects on patient care as well as increased associated costs. Importantly, the increase in hospital patient boarding has created critical shortcomings in disaster preparedness by limiting the capacity of emergency departments to respond to mass casualty incidents due to space and staffing constraints.
View Article and Find Full Text PDFResponse to "Anti-amyloid-beta treatments in Alzheimer's disease: When neurologists turn into cheerleaders".
Clin Neurol Neurosurg
January 2025
University of Southern California, Los Angeles, CA, United States. Electronic address:
Responses to the 2022 Infant Formula Shortage in the US by Race and Ethnicity.
J Nutr Educ Behav
January 2025
Economic Research Service, US Department of Agriculture.
Objective: Describe experiences of, and responses to, 2022 infant formula shortages among households with infants aged up to 18 months by race/ethnicity using Household Pulse Survey data.
Methods: Outcomes included whether households were affected by shortages and, if so, 3 nonmutually exclusive response categories (increased breastmilk, obtained formula atypically, and disruptive coping [disruptions to breastmilk and/or formula]) and 1 mutually exclusive response category (solely disruptive coping). Unadjusted shares reporting each were compared using t tests.
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