Microbial infections activate the innate and adaptive immune systems. Pathogen-associated molecular patterns produced by microbes, such as double-stranded RNA, are detected by PRRs (pattern-recognition receptors), such as toll-like receptor 3, and this leads to the expression of interferons and cytokines..
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC10883617 | PMC |
http://dx.doi.org/10.1161/ATVBAHA.123.320144 | DOI Listing |
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