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Characterization and angiogenic potential of CD146 endometrial stem cells.
Stem Cell Res Ther
September 2024
Department of Stem Cells & Regenerative Medicine, D.Y. Patil Education Society (Deemed to be University), D. Y. Patil Vidyanagar, Kasab Bawada, Kolhapur, 416006, Maharashtra, India.
Article Synopsis
- - The study investigates the role of endometrial stem cells (eSCs) in tissue regeneration and angiogenesis, particularly focusing on CD146 as a key marker that enhances the regenerative and vascular growth potential of these cells.
- - Researchers isolated eSCs from biopsies of active reproducing women and conducted various analyses to assess their properties, including growth factor secretion and angiogenic capabilities, using functional assays.
- - The findings potentially pave the way for innovative eSC-based therapies in regenerative medicine and the treatment of vascular disorders by understanding CD146's influence on eSCs' angiogenic functions.
Use of Intravenous Albumin: A Guideline From the International Collaboration for Transfusion Medicine Guidelines.
Chest
August 2024
Department of Medicine, University of Toronto, Mount Sinai Hospital, Toronto, ON, Canada; Transfusion Medicine Laboratory, Mount Sinai Hospital, Toronto, ON, Canada.
Article Synopsis
- Albumin is commonly used in various clinical settings for improving blood flow, fluid removal, and managing cirrhosis complications, leading to guidelines created by the International Collaboration for Transfusion Medicine.
- A dedicated panel, including researchers and a patient representative, developed these guidelines based on a systematic review of existing studies, resulting in 14 recommendations for adult and pediatric critical care, cardiovascular surgery, kidney therapy, and cirrhosis management.
- Most recommendations (12 out of 14) advised against widespread albumin usage in many scenarios, highlighting a lack of strong evidence, with only two recommendations suggesting conditional use in specific cirrhosis cases.
The 2023 AABB international guidelines for red blood cell transfusions: What is new?
Transfusion
April 2024
Department of Medicine, Rutgers Robert Wood Johnson Medical School, New Brunswick, New Jersey, USA.
AABB recommends restrictive RBC transfusions for hospitalized adults and children.
Ann Intern Med
February 2024
Warren Alpert Medical School of Brown University and Lifespan Cardiovascular Institute, Providence, RI, USA (J.D.A., S.V.).
Carson JL, Stanworth SJ, Guyatt G, et al. JAMA. 2023;330:1892-1902.
View Article and Find Full Text PDFDevelopment and utility of SSR markers based on sp. whole-genome in triangle of U.
Front Plant Sci
January 2024
Group of Vegetable Breeding, Hainan Institute of Zhejiang University, Sanya, China.
Introduction: Simple sequence repeats (SSR), also known as microsatellites, are crucial molecular markers in both animals and plants. Despite extensive previous research on SSRs, the development of microsatellite markers in Brassica crops remains limited and inefficient.
Methods: Krait software was used to identify microsatellites by genome-wide and marker development based on three recently sequenced basic species of crops in the triangle of U ( rapa, and ), as well as three allotetraploids ( and ) using public databases.
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