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START: A Versatile Platform for Bacterial Ligand Sensing with Programmable Performances.
Adv Sci (Weinh)
September 2024
Department of Life Sciences, Pohang University of Science and Technology, Pohang, 37673, South Korea.
Recognition of signaling molecules for coordinated regulation of target genes is a fundamental process for biological systems. Cells often rely on transcription factors to accomplish these intricate tasks, yet the subtle conformational changes of protein structures, coupled with the complexity of intertwined protein interaction networks, pose challenges for repurposing these for bioengineering applications. This study introduces a novel platform for ligand-responsive gene regulation, termed START (Synthetic Trans-Acting Riboswitch with Triggering RNA).
View Article and Find Full Text PDFA major challenge in plastic recycling is to convert plastic waste into a useful product. For this transformation, sustainable technologies such as plastic recycling machines are required. Current technological concepts of plastic recycling are fairly similar.
View Article and Find Full Text PDFFebruary 6, Kahramanmaraş earthquakes and the disaster management algorithm of adult emergency medicine in Turkey: An experience review.
Turk J Emerg Med
April 2024
Department of Emergency Medicine, Kocaeli University Faculty of Medicine, Kocaeli, Turkey.
This compilation covers emergency medical management lessons from the February 6 Kahramanmaraş earthquakes. The objective is to review relevant literature on emergency services patient management, focusing on Koenig's 1996 Simple Triage and Rapid Treatment (START) and Secondary Assessment of Victim Endpoint (SAVE) frameworks. Establishing a comprehensive seismic and mass casualty incident (MCI) protocol chain is the goal.
View Article and Find Full Text PDFWomen's sexual health improvement: sexual quality of life and pelvic floor muscle assessment in asymptomatic women.
Front Med (Lausanne)
February 2024
Department of Gynecology, Medical University of Lublin, Lublin, Poland.
Introduction: Problems related to the quality of sexual life in gynecological practice are usually neglected. This study aimed to highlight the significance of this area of concern and evaluate the usefulness of tools, such as patient-reported outcomes (PROs) and pelvic floor examination, to improve women's sexual wellbeing and to identify predictors of poor quality of sexual life during the well-woman annual visit.
Methods: A cross-sectional study was designed to examine 300 healthy women to determine whether the sexual quality of life (SQOL) questionnaire (on electronic devices) and pelvic floor muscle assessment (the vulva, anus, muscles, and periurethral (VAMP) protocol) of asymptomatic women during the annual bimanual examination (BME) help differentiate patients who would benefit from discussing sexual problems with a gynecologist.
START-A (Simple Triage, Rapid Treatment and Analgesia) in Mass Casualty Incidents.
Wilderness Environ Med
June 2024
Department of Emergency Medicine, Kartal Dr. Lutfi Kirdar City Hospital, University of Health Sciences, Turkey.
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