Purpose: To explore intraocular pressure (IOP) and its associated parameters in an aged population.
Methods: The epidemiologic Ural Very Old Study (UVOS) conducted in Bashkortostan/Russia included 1526 participants with an age of ≥85 years. Besides a whole series of ocular and systemic examinations, IOP was determined applying non-contact tonometry. Body mass index, diastolic blood pressure and age were the factors used to estimate the cerebrospinal fluid pressure (CSFP).
Results: The study consisted of 904 participants (age: 88.6 ± 2.7 years) with available IOP readings and without anti-glaucomatous therapy. Mean IOP was 14.5 ± 5.1 mmHg (median: 14 mm Hg; Q1:11; Q3:16; 95%CI:8,25) and 14.8 ± 4.6 mmHg (median: 14 mm Hg; Q1:12; Q3:17; 95%CI:8,28) in the right and left eyes, respectively. Higher IOP correlated (multivariable analysis; correlation coefficient r:0.32) with female sex ( < 0.001), more sedentary lifestyle ( = 0.006), higher estimated CSFP ( < 0.001), higher total protein serum concentration ( < 0.001), stronger hand grip force ( = 0.01), thicker central cornea ( < 0.001), longer axial length ( = 0.01), absence of previous cataract surgery ( = 0.001), higher degree of pseudoexfoliation ( = 0.02, and thinner peripapillary retinal nerve fiber layer thickness ( = 0.004). Using this that model, IOP reading enlarged by 0.22 mmHg (95% CI: 0.09, 0.35) for each increase in estimated CSFP by 1 mm Hg, by 0.03 mm Hg (95% CI: 0.02,0.05) for each thickening in central corneal thickness by 1 μm, by 0.56 mm Hg (95%CI: 0.13,1.00) for each axial elongation by 1 mm, and by 0.40 mmHg (95% CI: 0.06,0.74) for each increase in the degree of pseudoexfoliation, and it decreased by 0.40 mmHg (95% CI: 0.06,0.74) by cataract surgery.
Conclusions: In this study population aged 85+years, IOP readings showed similar relationships as in younger study populations, including positive associations with higher estimated CSFP and longer axial length and a negative association with cataract surgery.
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http://dx.doi.org/10.1016/j.heliyon.2024.e25794 | DOI Listing |
Arch Soc Esp Oftalmol (Engl Ed)
December 2024
Servicio Oftalmología, Hospital Alfredo Espinosa, Urduliz, Bizkaia, Spain.
A 66-year-old woman presents with unilateral orbital inflammation of several years of evolution, initially classified as idiopathic orbital inflammatory disease (IOID) subtype myositis. She presented with pain, eyelid inflammation and significant elevation of intraocular pressure, as well as radiological signs of exophthalmos and superior rectus myositis. She was treated with corticosteroids, with partial response.
View Article and Find Full Text PDFArch Soc Esp Oftalmol (Engl Ed)
December 2024
Departamento de Oftalmología, Hospital Universitario Virgen de la Macarena, Sevilla, Spain; Miembros de la «Red de Enfermedades Inflamatorias, Enfermedades Inflamatorias Oculares, Enfermedades Inflamatorias No Infecciosas de la Superficie Ocular, Instituto de Salud Carlos III (RICORS). FISS-21-RD21/0002/0011»; Área de Oftalmología, Departamento de Cirugía, Universidad de Sevilla, Sevilla, Spain.
Although silicone oil is used as an intraocular buffer in vitreoretinal surgical procedures, its use can cause complications, including glaucoma. This study highlights the importance of individualized approaches for the management of silicone oil-induced glaucoma. A 62-year-old man with a past medical history of retinal detachment and multiple ocular surgical procedurespresented with uncontrolled ocular pressure peaks after retinal detachment surgery using silicone oil as a buffer, which did not resolve after removal of the buffer.
View Article and Find Full Text PDFInt J Sport Nutr Exerc Metab
December 2024
Department of Physical Education and Sport, Faculty of Sport Sciences, University of Granada, Granada, Spain.
This study aimed to determine the impact of caffeine (200 mg), beta-alanine (3 g), and their combination on intraocular pressure (IOP), ocular perfusion pressure (OPP), and mean arterial pressure (MAP) at rest and after resistance training. Twenty young men (age = 23.4 ± 4.
View Article and Find Full Text PDFBMC Ophthalmol
December 2024
Department of Ophthalmology, Faculty of Medicine, Graduate School of Medicine, Hokkaido University, N-15, W-7, Kita-ku, Sapporo, 060-8638, Japan.
Background/aim: Mucosa-associated lymphoid tissue (MALT) lymphomas occur in not only the ocular adnexa, but rarely in the sclera or uvea. Histopathological confirmation contributes to a better understanding of the pathogenesis and treatment. We report a case of uveoscleral MALT lymphoma with angle-closure glaucoma.
View Article and Find Full Text PDFSci Rep
December 2024
Department of Ophthalmology, Rajavithi Hospital and College of Medicine, Rangsit University, Bangkok, Thailand.
Relative anterior microphthalmos (RAM) is a rare ocular condition characterized by disproportionately small anterior segments but normal axial length (corneal diameter < 11 mm and axial length > 20 mm). This study aimed to determine the prevalence of RAM and its association with glaucoma utilizing IOL Master 700 data (Carl Zeiss Meditec, Jena, Germany). A retrospective analysis was conducted of the biometric parameters of 6,407 eyes, and 115 cases of RAM were identified.
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