Electron beam melting is a powder bed fusion process capable of manufacturing thin structural features. However, as the thickness of these features approaches typical microstructure grain sizes, it becomes vital to understand how the manufacturing process contributes to local crystallographic texture and anisotropy in micromechanical response. Therefore, this article investigates Ti-6Al-4V ⍺/β-phase formation within thin components using a variety of experimental and numerical approaches. Optical and scanning electron microscopy are used to determine through-thickness distributions of prior-β width ([top, middle, bottom]:[81.2 ± 44.2, 76.02 ± 30.4, 75.6 ± 31.2] μm), ⍺-lath thickness ([top, middle, bottom]:[1.0 ± 1.3, 1.3 ± 1.2, 1.4 ± 1.8] μm; average), and ⍺/β-phase fractions ([top, middle, bottom]:[0.87 ± 0.05, 0.82 ± 0.03, 0.88 ± 0.03]; average). Manufacturing process (i.e., "logfile") data is used within a layer-by-layer finite element "birth/death" model. This model is loosely coupled with the Kim-Kim-Suzuki phase field model and a CALPHAD thermodynamic database to predict ⍺-lath growth throughout the process. In general, good correlation is found between the experimental data and the predicted temperature history, ⍺-lath coarsening, and phase fraction. This indicates that these tools would be useful in predicting process-structure-properties-performance relationships for thin features.
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http://dx.doi.org/10.1016/j.heliyon.2024.e25971 | DOI Listing |
BMJ Oncol
September 2023
Department of Big Data in Health Science, School of Public Health and The Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
Objective: This study aimed to explore the global burden of early-onset cancer based on the Global Burden of Disease (GBD) 2019 study for 29 cancers worldwid.
Methods And Analysis: Incidence, deaths, disability-adjusted life years (DALYs) and risk factors for 29 early-onset cancer groups were obtained from GBD.
Results: Global incidence of early-onset cancer increased by 79.
BMJ Oncol
April 2024
National Cancer Institute, Center for Global health, Rockville, Maryland, USA.
Introduction: Research is an essential pillar of cancer control and key in shaping regional cancer control agendas. Imbalances in science and technology in terms of lack of female participation have been well documented. However, there is little evidence about country-level female participation in cancer research.
View Article and Find Full Text PDFFront Cell Infect Microbiol
January 2025
Department of Clinical Laboratory, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Background: Though droplet digital PCR (ddPCR) has emerged as a promising tool for early pathogen detection in bloodstream infections (BSIs), more studies are needed to support its clinical application widely due to different ddPCR platforms with discrepant diagnostic performance. Additionally, there is still a lack of clinical data to reveal the association between pathogen loads detected by ddPCR and corresponding BSIs.
Methods: In this prospective study, 173 patients with suspected BSIs were enrolled.
BMC Psychol
January 2025
Nursing Research Center, Kerman University of Medical Sciences, Kerman, Iran.
Background: Long-term care of patients with schizophrenia, which creates a burden of care, leads to disruption in interactions, social and personal relationships, changes in lifestyle, and shifts in the roles of family members. This study aimed to explore the lived experiences of family caregivers who are caring for a family member with schizophrenia within the Baloch ethnicity.
Methods: This is a qualitative study, using a descriptive phenomenological approach.
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