High Signal to Noise Ratio Piezoelectric Thin Film Sensor Based on Elastomer Amplification for Ambulatory Blood Pressure Monitoring.

ACS Sens

Key Laboratory for Biomechanics and Mechanobiology of Ministry of Education, Beijing Advanced Innovation Center for Biomedical Engineering, School of Biological Science and Medical Engineering, School of Engineering Medicine, Beihang University, Beijing 100191, China.

Published: March 2024

AI Article Synopsis

  • * A study indicated that increasing the Young's modulus and thickness of the elastic medium reduces the amplitude of pulse sensing signals.
  • * By creating a theoretical model and optimizing the sensor, the researchers achieved a 480% increase in pulse wave signal amplitude, highlighting the potential for improved ambulatory blood pressure monitoring.

Article Abstract

Continuous pulse wave detection can be used for monitoring and diagnosing cardiovascular diseases, and research on pulse sensing based on piezoelectric thin films is one of the hot spots. Usually, piezoelectric thin films do not come into direct contact with the skin and need to be connected through a layer of an elastic medium. Most views think that the main function of this layer of elastic medium is to increase the adhesion between the sensor component and the skin, but there is little discussion about the impact of the elastic medium on pulse vibration transmission. Here, we conducted a detailed study on the effects of Young's modulus and the thickness of elastic media on pulse sensing signals. The results show that the waveform amplitude of the piezoelectric sensing signal decreases with the increase of Young's modulus and thickness of the elastic medium. Then, we constructed a theoretical model of the influence of elastic media on pulse wave propagation. The amplitude of the pulse wave signal detected by the optimized sensor was increased to 480%. Our research shows that by regulating Young's modulus and thickness of elastic media, pulse wave signals can undergo a similar amplification effect, which has an important theoretical reference value for achieving ambulatory blood pressure monitoring based on high-quality pulse waves.

Download full-text PDF

Source
http://dx.doi.org/10.1021/acssensors.3c02180DOI Listing

Publication Analysis

Top Keywords

pulse wave
16
elastic medium
16
piezoelectric thin
12
young's modulus
12
modulus thickness
12
thickness elastic
12
elastic media
12
media pulse
12
ambulatory blood
8
blood pressure
8

Similar Publications

Intradermal Advanced Glycation End-products Relate to Reduced Sciatic Nerve Structural Integrity in Type 2 Diabetes.

Clin Neuroradiol

January 2025

Department of Endocrinology, Diabetology, Metabolic Diseases and Clinical Chemistry (Internal Medicine 1), Heidelberg University Hospital, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany.

Background: Cardiovascular risk management is beneficial, but stringent glycemic control does not prevent the progression of distal sensorimotor polyneuropathy (DSPN). Persistent hyperglycemia-induced alterations and cardiovascular factors may contribute to diabetes-associated nerve damage. This study aimed to evaluate the correlation between skin auto-fluorescence (sAF), an indicator of dermal advanced glycation end-product (AGE) accumulations, cardiovascular risk, and changes in peripheral nerve integrity.

View Article and Find Full Text PDF

Association of plasma aldosterone concentration with arterial stiffness progression in hypertensive patients: insights from a longitudinal analysis.

Postgrad Med

January 2025

Hypertension Center of People's Hospital of Xinjiang Uygur Autonomous Region, Xinjiang Hypertension Institute, NHC Key Laboratory of Hypertension Clinical Research, Key Laboratory of Xinjiang Uygur Autonomous Region, Hypertension Research Laboratory, Xinjiang Clinical Medical Research Center for Hypertension (Cardio-Cerebrovascular) Diseases, Urumqi, China.

Purpose: Limited studies have examined the relationship between plasma aldosterone concentration (PAC) and arterial stiffness progression. This study aimed to investigate the longitudinal association between baseline PAC and arterial stiffness progression in hypertensive patients.

Patients And Methods: This was a longitudinal study conducted at the Hypertension Center of People's Hospital of Xinjiang Uygur Autonomous Region between April 2020 and October 2023.

View Article and Find Full Text PDF

Background: The vascular and cardiometabolic effects of pecans are relatively under-studied.

Objectives: The aim was to examine how substitution of usual snack foods with 57 g/day of pecans affects vascular health, risk factors for cardiometabolic diseases and diet quality, compared to continuing usual intake in individuals at risk for cardiometabolic diseases.

Methods: A 12-week single-blinded, parallel, randomized controlled trial was conducted.

View Article and Find Full Text PDF

Microcavity exciton polaritons (polaritons) as part-light part-matter quasiparticles garner considerable attention for Bose-Einstein condensation at elevated temperatures. Recently, halide perovskites have emerged as promising room-temperature polaritonic platforms because of their large exciton binding energies and superior optical properties. However, currently, inducing room-temperature nonequilibrium polariton condensation in perovskite microcavities requires optical pulsed excitations with high excitation densities.

View Article and Find Full Text PDF

Soliton Dynamics over a Disordered Topography.

Phys Rev Lett

December 2024

MSC, CNRS, Université Paris Cité, UMR 7057, F-75013 Paris, France.

We report on the dynamics of a soliton propagating on the surface of a fluid in a 4-m-long canal with a random or periodic bottom topography. Using a full space-and-time resolved wave field measurement, we evidence, for the first time experimentally, how the soliton is affected by the disorder, in the context of Anderson localization, and how localization depends on nonlinearity. For weak soliton amplitudes, the localization length is found in quantitative agreement with a linear shallow-water theory.

View Article and Find Full Text PDF

Want AI Summaries of new PubMed Abstracts delivered to your In-box?

Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!